Results 91 to 100 of about 5,999,057 (304)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Direct PCR for DNA barcoding of Bulbophyllum lobbii Lindl. based on rbcL sequence [PDF]

BIO Web of Conferences
DNA barcoding is a molecular technique frequently used to identify or confirm a species, which involves the steps of isolation, amplification via PCR, and sequencing analysis.
Su’udi Mukhamad, Bahrul Ulum Fuad, Setyati Dwi   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Cognitive control of sequential knowledge in 2-year-olds: evidence from an incidental sequence-learning and generation-task [PDF]

, 2007
Thirty-eight two-year-olds were trained under incidental instructions on a six element deterministic sequence of spatial locations. Following training, participants were informed of the presence of a sequence and asked to either reproduce or suppress the
Bremner, Andrew J.; id_orcid, Bremner, Andrew, Kotsoni, E., Mareschal, Denis, Johnson, M.H., Cleeremans, Axel, Mareschal, D., Destrebecqz, Arnaud, Bremner, Andrew J., Csibra, Gergely   +9 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

SeqDoC: rapid SNP and mutation detection by direct comparison of DNA sequence chromatograms

BMC Bioinformatics, 2005
Background This paper describes SeqDoC, a simple, web-based tool to carry out direct comparison of ABI sequence chromatograms. This allows the rapid identification of single nucleotide polymorphisms (SNPs) and point mutations without the need to install ...
Crowe Mark L
doaj   +1 more source

WTO direct action convergence, Seattle, WA (nov. 20-28), registration application [verso]

, 1999
Alternate title: DAN registration. Affiliated web page url: www.agitprop.org/artandrevolution/wto. Also sent out as document 6 of 19 in a Direct Action Network (DAN) organizing packet; these documents are contained in a 9 X 12 inch envelope stating ...
Direct Action Network (DAN)
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Performance analysis of DSSS system with periodic sequence against CW interference1

Tongxin xuebao, 2007
Based on the brief account of the performance analysis result of direct sequence spread spectrum（DSSS） system against single tone continuous wave（CW） interference obtained from the traditional stand Gaussian approximation（SGA） hypothesis,the mathematical
WEI An-quan1, SHEN Lian-feng 1
doaj   +2 more sources