Results 111 to 120 of about 50,934 (264)

AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint

Advanced Science, EarlyView.
AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz, Saurabh Upadhyay, Renjie Zhu, Hongliang Duan, Moustafa T. Gabr   +4 more
wiley   +1 more source

Optimizing dosimetry in Y-90 microsphere radioembolization: GPU-accelerated Monte Carlo simulation versus conventional methods for high-volume setting

EJNMMI Physics
Background Yttrium-90 (90Y) microsphere radioembolization has shown unique advantages in treating both primary and metastatic liver cancer and was introduced into China in 2022.
Liu Hongming, Liang Ziwei, Hu Ziyi, Qu Shuiyin, Hu Ankang, Yan ShuChang, Wu Zhen, Zhang Hui, Li Junli, Qiu Rui   +9 more
doaj   +1 more source

High-resolution rapid calculation method of neutron spectrum based on energy response

Nuclear Engineering and Technology
Conventional neutron spectrum calculation methods are difficult to achieve both high resolution and high efficiency. This paper presents a high-resolution rapid calculation method of neutron spectrum.
Dongyuan Li, Qingquan Pan, Xiaojing Liu
doaj   +1 more source

Sub‐Terahertz Memristor Switches Using MoS2 by Liquid–Liquid Interface Assembly

Advanced Science, EarlyView.
This work introduces application‐ready sub‐terahertz memristor switches fabricated from electrochemically exfoliated MoS2 nanosheets assembled at a liquid–liquid interface. The devices exhibit robust unipolar resistive switching, low insertion loss, and high isolation across 10–110 GHz.
Tomás Mingates, Mohamed E. Ghatas, Jonas Deuermeier, Adam G. Kelly, Joseph Neilson, Jonathan N. Coleman, Luís Mendes, João C. Vaz, Sérgio Matos, Luca Lucci, Antonio Clemente, Zdeněk Sofer, Luís M. Pessoa, Elvira Fortunato, Rodrigo Martins, Asal Kiazadeh   +15 more
wiley   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

Advanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg, Irina Wachter, Agnieszka Pancholi, Matthias Akyel, Yomna Gohar, Priya Kumar, Ana Miguel Fernandes, Yuzhi Bao, Alica Schmidt‐Heydt, Marcel Piepers, Alicia Günthel, Marcel Sobucki, Elisa Kämmer, Süheyla Eroğlu‐Kayıkçı, Stephan Allgeier, Sylvia Erhardt, Vasily Zaburdaev, Carmelo Ferrai, Lennart Hilbert   +18 more
wiley   +1 more source

Applying new hybrid method of analytical hierarchy process, Monte Carlo Simulation and PROMETHEE to prioritize and selecting appropriate target market

تحقیقات بازار یابی نوین, 2015
Making decision to choose the appropriate target market is one of the key decisions in the success of firms, which has direct effect in the amount of their profits.
Amir Kariznoee, Zahra Naji-Azimi, Alireza Pooya   +2 more
doaj  

Numerical analysis of gas exhaust in Wendelstein 7-X using the direct simulation Monte Carlo method

Nuclear Fusion
The present work is focused on a 3D numerical assessment of the Wendelstein 7-X (W7-X) particle exhaust. For all the numerical simulations the direct simulation Monte Carlo solver of the DIVGAS workflow, has been employed.
S. Varoutis, C. Tantos, H. Strobel, D. Boeyaert, Y. Igitkhanov, F. Litovoli, C.P. Dhard, V. Haak, D. Naujoks, the W7-X Team   +9 more
doaj   +1 more source

Sparse Pd–Te Covalent Bridges Drive Anomalous Bulk‐to‐Monolayer Electronic and Magnetic Evolution in FePd2Te2

Advanced Science, EarlyView.
Bulk FePd2Te2 contains sparse interlayer Pd–Te covalent bonds, giving it unexpectedly low exfoliation energy and enabling van der Waals‐like exfoliation. Cleaving these bonds during exfoliation makes the monolayer magnetically distinct from the bulk: magnetic anisotropy energy increases, and the strain‐response coefficient of the magnetic moment ...
Huaiyuan Zhao, Jianwen Fang, Mohan Luo, Yinuo Ye, Yulin Wang, Jianhui Yang, Hongwen Zhang, Peng Cheng   +7 more
wiley   +1 more source

Monte Carlo simulation applied to order economic analysis Simulação de Monte Carlo aplicada à análise econômica de pedido

Production, 2011
The use of mathematical and statistical methods can help managers to deal with decision-making difficulties in the business environment. Some of these decisions are related to productive capacity optimization in order to obtain greater economic gains for
Abraão Freires Saraiva Júnior, Cristiane de Mesquita Tabosa, Reinaldo Pacheco da Costa   +2 more
doaj  

Enhanced fidelity of Monte Carlo coupled multi-physics simulations in the MCS code

Nuclear Engineering and Technology
This study integrates previously developed methods to enhance the fidelity of direct whole-core Monte Carlo coupled multi-physics simulations in the MCS code. First, it introduces multi-physics simulations with spatially continuous material properties by
Muhammad Imron, Deokjung Lee
doaj   +1 more source