Results 131 to 140 of about 7,097,775 (327)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Le discours direct dans la presse : une approche didactique
E-REA, 2019 This paper offers a synthesis of recent research works focusing on direct reported speech used in the British press. Thanks to a didactic approach, it aims to analyse the way reported words are inserted into newspaper articles.
Grégoire LACAZE
doaj +1 more source
, 2017 Child-directed speech (CDS) is a talking style adopted by caregivers when they talk to toddlers (Snow, 1995). We consider the role of distributional semantic features of CDS in language acquisition. We view semantic structure as a manifold on which words lie.
Sun, Hao, Pate, John
openaire +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Directive Speech Acts Found in “5cm” Movie [PDF]
, 2014 Keywords: Speech Acts, Direct and Indirect directive, 5cm MovieSpeech acts is the study of intended meaning the utterances speaker or writer. Speech acts include locutionary acts, illocutionary force, and perlocutionary effect.
KUSUMAWATI, W. (WIDYAYU)
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Disfluency in child-directed speech
, 2013 Modelling the emergence of linguistic structures in early ...
Nilsson Björkenstam, Kristina +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
A Speech Act Analysis of Direct Utterances on Short Story the Enchancted Fish [PDF]
, 2015 Direct utterance is usually used in daily conversation. This research is aimed at (1) identifying the mode of the direct sentences on short story entitled the Enchanted Fish, (2) describing the purposes of the direct utterances in short story entitled ...
Dwina, L. (Lasma)
core
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source