Comment on "Psychometric Performance of Clinician- and Patient-Reported Outcome Measures in Surgically Treated Thoracic Myelopathy: A Multicenter Prospective Study". [PDF]
Deng J, Xiao Y, Lin H.
europepmc +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Direct Z-scheme ZnI<sub>2</sub>/GeTe van der Waals heterostructure for photocatalytic overall water splitting. [PDF]
Kashif M, Shahzad A, -Rehman AU.
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Rethinking Vaginal Microbiome Resilience: A Conceptual Multi-Omic Framework. [PDF]
Cagle-White B +4 more
europepmc +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Morphology-Guided Surgical Management of Complex Traumatic Hip Fracture-Dislocations and Acetabular Fractures: A Six-Case Series Illustrating Morphology-Based Surgical Approaches. [PDF]
Singh NS, Bisht M, Saxena R.
europepmc +1 more source

