Results 61 to 70 of about 11,092,830 (279)

Patient-specific anatomical model for deep brain stimulation based on 7 Tesla MRI. [PDF]

PLoS ONE, 2018
OBJECTIVE:Deep brain stimulation (DBS) requires accurate localization of the anatomical target structure, and the precise placement of the DBS electrode within it.
Yuval Duchin, Reuben R Shamir, Remi Patriat, Jinyoung Kim, Jerrold L Vitek, Guillermo Sapiro, Noam Harel   +6 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Compact High‐Power Visible Laser Diode Wavelength Division Multiplexing for White‐Light Communication

Advanced Photonics Research, 2021
For compact ultrahigh‐power lighting and high‐speed optical wireless communication (OWC) purposes, the red/green/violet laser diodes (R/G/V‐LDs) moduled with specific Subminiature A (SMA) connectors are used for cold white‐light mixing and direct digital
Chia-Yu Su, Huai-Yung Wang, Chih-Hsien Cheng, Gong-Ru Lin   +3 more
doaj   +1 more source

A Multidirectional Occlusion Shading Model for Direct Volume Rendering [PDF]

Computer Graphics Forum, 2010
AbstractIn this paper, we present a novel technique which simulates directional light scattering for more realistic interactive visualization of volume data. Our method extends the recent directional occlusion shading model by enabling light source positioning with practically no performance penalty.
Veronika Soltészová, Daniel Patel, Stefan Bruckner, Ivan Viola   +3 more
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Visualization of Segmented Structures in 3D Multimodal Medical Data Sets

Advances in Electrical and Computer Engineering, 2011
The simultaneous inspection of images obtained using different medical scanning methods represents a common practice for accurate medical diagnosis. The term multimodality refers to multiple medical data sets obtained by scanning a patient with the ...
HERGHELEGIU, P., GAVRILESCU, M., MANTA, V.   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Enhancing Urban Landscape Design: A GAN-Based Approach for Rapid Color Rendering of Park Sketches

Land
In urban ecological development, the effective planning and design of living spaces are crucial. Traditional color plan rendering methods, mainly using generative adversarial networks (GANs), rely heavily on edge extraction.
Ran Chen, Jing Zhao, Xueqi Yao, Yueheng He, Yuting Li, Zeke Lian, Zhengqi Han, Xingjian Yi, Haoran Li   +8 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source