Results 111 to 120 of about 20,647 (260)

Generalizing the Gaussian Network Model: Spanning‐Tree Thermodynamics Shows Entropy‐Driven KRAS Activation

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The GTPase KRAS executes a conformational switch between a GTP‐bound active state and a GDP‐bound inactive state, a process central to oncogenic signaling. However, the structural basis of this switching at the level of residue‐contact organization remains incompletely characterized by traditional binary structural models.
Fatma Senguler Ciftci, Burak Erman
wiley   +1 more source

Why theory matters for causal inference? Rethinking endogeneity in entrepreneurship research

open access: yesStrategic Entrepreneurship Journal, EarlyView.
Abstract Endogeneity in entrepreneurship research is often treated as a statistical complication addressable through advanced econometric tools. This commentary argues that such an approach overlooks a deeper issue: endogeneity is conceptual before it is statistical.
Daniel Tzabbar
wiley   +1 more source

From prediction to intervention: Paradigm shifts in causal AI for precision medicine and large‐scale cohorts

open access: yesVIEW, EarlyView.
Large‐scale cohorts and multimodal biomedical data have enabled powerful predictive models for clinical risk stratification, but prediction alone cannot guide effective interventions. This review introduces causal artificial intelligence as a design‐first framework that integrates target trial emulation, causal discovery, and robust effect estimation ...
Linlin Cao   +5 more
wiley   +1 more source

Graph neural network‐based attack prediction for communication‐based train control systems

open access: yesCAAI Transactions on Intelligence Technology, EarlyView.
Abstract The Advanced Persistent Threats (APTs) have emerged as one of the key security challenges to industrial control systems. APTs are complex multi‐step attacks, and they are naturally diverse and complex. Therefore, it is important to comprehend the behaviour of APT attackers and anticipate the upcoming attack actions.
Junyi Zhao   +3 more
wiley   +1 more source

Detecting abnormal connectivity in schizophrenia via a joint directed acyclic graph estimation model. [PDF]

open access: yesNeuroimage, 2022
Zhang G   +8 more
europepmc   +1 more source

Directed Acyclic Graph Convolutional Networks

open access: yesIEEE Transactions on Signal Processing
Directed acyclic graphs (DAGs) are central to science and engineering applications including causal inference, scheduling, and neural architecture search. In this work, we introduce the DAG Convolutional Network (DCN), a novel graph neural network (GNN) architecture designed specifically for convolutional learning from signals supported on DAGs.
Samuel Rey   +2 more
openaire   +2 more sources

Education, Skills, and Intergenerational Inequality in Status Attainment: Causal Mediation Analysis and Typology of 23 OECD Countries

open access: yesThe British Journal of Sociology, EarlyView.
ABSTRACT Scholars have long investigated intergenerational inequality, with attention to the associations among social origins, education, and socio‐economic destinations: the so‐called OED triangle. Meanwhile, recent research highlights distinct roles of education and skills in status attainment.
Satoshi Araki
wiley   +1 more source

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