Scalable computation of ultrabubbles in pangenomes by orienting bidirected graphs. [PDF]
Harviainen J +5 more
europepmc +1 more source
Patients with oculopharyngeal muscular dystrophy exhibit disease‐specific salivary hyperviscosity that tracks with dysphagia severity and airway invasion. Non‐invasive chairside screening of salivary viscosity may enable clinicians to stratify aspiration risk during routine care to prevent severe pulmonary complications.
Alex Zvulunov +9 more
wiley +1 more source
Moral hazard induced unraveling: Theory and evidence from the Affordable Care Act
Abstract We identify and quantify a new form of welfare loss in insurance markets. We first show theoretically that moral hazard from subsidies for cost‐sharing combined with community rating mimics adverse selection and can unravel insurance markets.
Cameron M. Ellis +2 more
wiley +1 more source
Causal mediation analysis of contact with COVID-19 patients and burnout syndrome in physiotherapists in Japan: secondary analysis of a multicentre observational study. [PDF]
Nojiri S +5 more
europepmc +1 more source
Fairness‐aware insurance pricing: A multi‐objective optimization approach
Abstract Machine‐learning models can provide accurate predictions in insurance pricing, but can also increase disparities between protected groups. Existing fairness‐aware pricing approaches typically target one fairness notion at a time, making it difficult to compare trade‐offs between predictive accuracy, group fairness, individual fairness, and ...
Tim J. Boonen, Xinyue Fan, Zixiao Quan
wiley +1 more source
A Principled Framework for Mendelian Randomization in Oral Health Research
This methodological article provides a clear and accessible overview of Mendelian randomization for oral health researchers, emphasizing the core assumptions needed for credible causal inference. Focusing on applications in oral health, particularly periodontitis, it highlights both the strengths and limitations of the study design in order to support ...
Nasir Z. Bashir +5 more
wiley +1 more source
Advanced analysis of formulation parameters governing encapsulation efficiency: drug delivery system. [PDF]
Sumayli A, Alqahtani SS.
europepmc +1 more source
Cross‐Sectional Studies: Strengths, Limitations, and Methodological Considerations
Cross‐sectional studies measure variables at a single time point to estimate prevalence and support descriptive epidemiology ‐ characterizing population health, tracking trends via repeated surveys – and for developing and validating screening instruments and diagnostic models.
Sebastian‐Edgar Baumeister +4 more
wiley +1 more source
Evolutionary signals in metabolic networks of insect endosymbionts revealed through comparative topological modeling. [PDF]
Reyes-Prieto M +7 more
europepmc +1 more source
The target trial framework is a pragmatic roadmap for observational causal inference that clarifies questions, mitigates time‐related bias, and improves interpretability while acknowledging limits. With transparent protocols, appropriate methods, and suitable data, it can complement randomized trials and inform practice and policy.
Sebastian‐Edgar Baumeister +6 more
wiley +1 more source

