Results 131 to 140 of about 1,437,233 (261)
Task scheduling for directed cyclic graph using matching technique
, 2015 The scheduling and mapping of task graph to processors is considered to be the most crucial NP-complete in parallel and distributed computing systems.
Ariffin, Wan Nor Munirah +1 more
core +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Force-Directed 3D Arc Diagrams
, 2014 We discuss a force-directed algorithm for constructiong 3D arc diagrams. We introduce forces that allow curves in a 2D force directed graph to bow out and away from each other in the third dimension in order to achieve better angular ...
Bannister, Michael J. +2 more
core
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Multidecompositions of Complete Directed Graphs into Directed Graph Pairs
, 2019 A directed graph is a way to encode information about directional relationships among objects. The complete directed graph on n objects is the directed graph with arrows pointing in both directions for each pair of objects.
Ward, Patrick
core
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Graph Drawing Techniques for Geographic Visualization [PDF]
, 2004 Geovisualizers often need to represent data that consists of items related together. Such data sets can be abstracted to a mathematical structure, the graph.
Rodgers, Peter
core
Graph-directed sprays and their tube volumes via functional equations
, 2017 WOS: 000406879400004The notion of sprays introduced by Lapidus and his co-workers has proved useful in the context of fractal tube formulas. In the present note, we define a notion of a graph-directed spray, associated with a weighted directed graph ...
Üreyen, Adem Ersin +8 more
core +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source