FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Study on the regional risk classification method for the prevention and control of emerging infectious diseases based on directed graph theory. [PDF]
Front Public Health, 2023 Liu Y, Wang X, Zhang C.
europepmc +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Directed graph mapping shows rotors maintain non-terminating and focal sources maintain self-terminating Torsade de Pointes in canine model. [PDF]
Front Physiol, 2023 Van Den Abeele R +7 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
New Approach for Closure Spaces on Graphs Based on Relations and Graph Ideals
AxiomsThe main aim of this paper is to combine the connections between graph theory and rough set theory. We created graph ideal ASs by proposing the interior and closure operators, utilizing the concept of graph ideals.
Rehab Alharbi +3 more
doaj +1 more source
Journal of Mathematics, 2017 The purpose of this paper is to present some existence and uniqueness results for common fixed point theorems for θ-ϕ contraction mappings with two metrics endowed with a directed graph.
P. Charoensawan, W. Atiponrat
doaj +1 more source
MDST-DGCN: A Multilevel Dynamic Spatiotemporal Directed Graph Convolutional Network for Pedestrian Trajectory Prediction. [PDF]
Comput Intell Neurosci, 2022 Liu S, Liu H, Wang Y, Sun J, Mao T.
europepmc +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Multiscale Principal Component Analysis-Signed Directed Graph Based Process Monitoring and Fault Diagnosis. [PDF]
ACS Omega, 2022 Ali H +5 more
europepmc +1 more source