Results 101 to 110 of about 839,618 (278)

Measuring the complexity of directed graphs: A polynomial-based approach.

open access: yesPLoS ONE, 2019
In this paper, we define novel graph measures for directed networks. The measures are based on graph polynomials utilizing the out- and in-degrees of directed graphs. Based on these polynomial, we define another polynomial and use their positive zeros as
Matthias Dehmer   +8 more
doaj   +1 more source

DiVenn: An Interactive and Integrated Web-Based Visualization Tool for Comparing Gene Lists

open access: yesFrontiers in Genetics, 2019
Gene expression data generated from multiple biological samples (mutant, double mutant, and wild-type) are often compared via Venn diagram tools. It is of great interest to know the expression pattern between overlapping genes and their associated gene ...
Liang Sun   +7 more
doaj   +1 more source

On Making Directed Graphs Transitive

open access: yesJournal of Computer and System Sciences, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Mathias Weller   +3 more
openaire   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Reconstruction of graph signals from traffic data on directed road networks using kernel methods

open access: yesApplied Network Science
The completeness of traffic data sets is endangered by distinct reasons, such as implementation costs or privacy concerns. Modelling an urban network as a road graph (i.e., with roads as nodes, and edges representing intersections) allows the use of ...
Rafael Alejandro Martínez Márquez   +1 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Tr-Span of Directed Wheel Graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2018
In this paper, we consider T-colorings of directed graphs. In particular, we consider as a T-set the set Tr = {0, 1, 2, . . ., r−1, r+1, . . .}. Exact values and bounds of the Tr-span of directed graphs whose underlying graph is a wheel graph are ...
Besson Marc, Tesman Barry
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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