Results 121 to 130 of about 382,964 (309)

Directed search of hypoglycemic compounds in the series of aroylpyruvic acid derivatives

open access: yesRUDN Journal of Medicine, 2010
The article deals with synthesis of new oxovanadium metal complexes in the series of esters and arylamides of aroylpyruvic acids. Comparative estimation of hypoglycemic activity of original ligands and obtained chelates is conducted.
N A Pulina   +3 more
doaj  

Evolving resource use for self-directed learning in physiology among first-year medical students in a classroom setting

open access: yesAdvances in Physiology Education
Self-directed learning (SDL) is integral to medical education. It helps in fostering critical thinking, independence, and problem-solving skills. With advancements in technology, digital tools like search engines, interactive content, and large language ...
Himel Mondal
doaj   +1 more source

Directed Search for Equilibrium Wage-Tenure Contracts [PDF]

open access: yes
I construct a theoretical framework in which firms offer wage-tenure contracts to direct the search by risk-averse workers. All workers can search, on or off the job. I characterize an equilibrium and prove its existence.
Shouyong Shi
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Directed search: Matching partners with pricing data

open access: yes, 2018
Search models have vastly improved our understanding of important market events that are not explained by classical economic theory, but they tend to treat price formation as an afterthought. This column introduces a survey of the literature on ‘directed
Wright, Randall   +3 more
core  

Estudo correlacional do inventário de busca auto dirigida (self-directed search) com o IFP

open access: yesPsicologia Escolar e Educacional
Este estudo investigou as correlações da versão brasileira do Self-Directed Search (SDS) de John L. Holland, com o Inventário Fatorial de Personalidade (IFP) avaliando um conjunto de necessidades conceituadas por Henrry Murray. O estudo foi realizado com
Ricardo Primi   +2 more
doaj   +3 more sources

Adults changing careers through university education: Making meaning of quantitative career assessment scores through an integrative structured interview

open access: yesSA Journal of Industrial Psychology, 2018
Orientation: Career change in adulthood is becoming a norm and university education is a pathway to new careers. Career psychologists are well positioned to assist adult career changers.
Mary McMahon   +2 more
doaj   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Multi-directional local search

open access: yesComputers & Operations Research, 2012
This paper introduces multi-directional local search, a metaheuristic for multi-objective optimization. We first motivate the method and present an algorithmic framework for it. We then apply it to several known multi-objective problems such as the multi-objective multi-dimensional knapsack problem, the bi-objective set packing problem and the bi ...
openaire   +4 more sources

Uniqueness of Equilibrium in Directed Search Models

open access: yesSSRN Electronic Journal, 2013
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kim, Jaehong, Camera, Gabriele
openaire   +3 more sources

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