Results 91 to 100 of about 175,658 (266)
The Synaxary of Andreas Kordopatis by Thanasis Valtinos was published serially in the magazine Tahydromos in 1964 and was first published in 1978 by Kedros Publications. In the first of two books about Kordopatis, subtitled America, Valtinos recounts the
Michaela Antoniou
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Literature, film and television - coexistence, antagonisms, influences [PDF]
This paper deals with the issue of the position of literature in relation to film and television in present times. The beginning of the 20th century was marked by the appearance of new media such as film and radio, and later on television.
Đorđević Milentije M.
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Directing and Puppetry in Contemporary Nigerian Theatre: A Study of the Production Final Draft
Studies that explore the arts of directing and puppetry are limited in Nigerian theatre. This article examines the directorial indices of a puppetry performance, Final Draft, directed by Ekeh Nneka Grace, on September 24, 2018, at the University of Port ...
Tekena Gasper Mark
doaj
Representation of War Events in the Creative Work of Theatre and Film Directors
The purpose of the article is to carry out a comprehensive analysis and identify the peculiarities of directorial creativity in Ukrainian theatre and cinema institutions in terms of reflecting the events of the Soviet- German war.
Галина Погребняк
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Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

