Results 161 to 170 of about 938,074 (307)

A unified strategy for remote C-H fluorination of phenylacetic acids and their homologues at the <i>meta</i>-position. [PDF]

Chem Sci
Zhou K, Chen X, Wang Y, Mao YJ, Yang X, Liu K, Pan Q, Pan DL, Xu DQ, Lou SJ.   +9 more
europepmc   +1 more source

Studies and analyses of space science problems related to the planning and directing of NASA lunar and planetary programs Third annual summary report, Jul. 1965 - Jun. 1966 [PDF]

Space science problems related to planning and directing NASA lunar and planetary programs - cost estimation, mission programming and goals, spacecraft technology, and trajectory ...

core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

<i>De novo</i> construction of C-O axial chirality <i>via</i> cobalt-catalyzed atroposelective C-H activation/annulation. [PDF]

Chem Sci
Zhang Y, Xie Y, Guo B, Dou Y, Yang D, Niu JL.   +5 more
europepmc   +1 more source

Annual Report for the Year Ending June 30, 1945 [PDF]

, 1946
Massachusetts. Board of Registration in Embalming and Funeral Directing.
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

One-Step Rh-Catalyzed Atom-Economical Cyclization of Acetophenones and Methyl Propiolate Affording Isoquinoline Derivatives. [PDF]

ACS Omega
Zeng F, Cai Y, Xiao Y, Xu H, Hong Y, Gao J, Fang J, Zeng Q, Su X.   +8 more
europepmc   +1 more source

The Grace of Directing the Exercises [PDF]

, 2015
Coble, Scott, S.J.
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides. [PDF]

J Pept Sci
Moriyama Y, Sada H, Nanjo T.
europepmc   +1 more source