Results 81 to 90 of about 117,629 (216)

A Transient Directing Group Strategy Enables Enantioselective Multicomponent Organofluorine Synthesis. [PDF]

J Am Chem Soc, 2021
Liu Z, Oxtoby LJ, Liu M, Li ZQ, Tran VT, Gao Y, Engle KM.   +6 more
europepmc   +1 more source

On directed groups [PDF]

Czechoslovak Mathematical Journal, 1960
openaire   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Transient directing group enabled Pd-catalyzed C-H oxygenation of benzaldehydes and benzylic amines. [PDF]

RSC Adv, 2022
Tian M, Shao L, Su X, Zhou X, Zhang H, Wei K, Sun R, Wang J.   +7 more
europepmc   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Synthesis of α-Branched Amines by Three- and Four-Component C-H Functionalization Employing a Readily Diversifiable Hydrazone Directing Group. [PDF]

Org Lett, 2021
Brandes DS, Muma AD, Ellman JA.
europepmc   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A "Traceless" Directing Group Enables Catalytic S_N2 Glycosylation toward 1,2-cis-Glycopyranosides. [PDF]

J Am Chem Soc, 2021
Ma X, Zheng Z, Fu Y, Zhu X, Liu P, Zhang L.   +5 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Palladium-Catalyzed Arylation of C(sp²)-H Bonds with 2-(1-Methylhydrazinyl)pyridine as the Bidentate Directing Group. [PDF]

ACS Omega, 2021
Wei J, Shao X, Zhao H, Yang H, Qiu S, Zhai H.   +5 more
europepmc   +1 more source