Results 51 to 60 of about 716,657 (292)

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Controlling AoA Estimation Errors in Rician Fading via Measurement Quality Classification

IEEE Access
Angle of Arrival (AoA) estimation plays a crucial role in modern positioning systems but is often affected by errors in multipath channels. Existing methods typically lack a direct mechanism to assess the quality of the estimates, while full channel ...
Pedro Lemos, Glauber Brante, Ohara Kerusauskas Rayel, Richard Demo Souza   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Cosmic Rays: The Second Knee and Beyond

, 2007
We conduct a review of experimental results on Ultra-High Energy Cosmic Rays (UHECR's) including measurements of the features of the spectrum, the composition of the primary particle flux and the search for anisotropy in event arrival direction.
Abbasi R U, Abbasi R U, Abbasi R U, Afanasiev B N Nagano M, AGASA Collaboration, Ave M, Berezinsky V S, Bergman D R, Bergman D R, Biermann P L Ahn E J G M T Stanev T, Bonifazi C, Bossa M, CERN, Douglas R Bergman, Egorova V P, Egorova V P, Farrar G R Piran T, Hayashida N, Hayashida N, Hayashida N, Heck D, Hess V F, Hinton J A, Ivanov A A, John W Belz, Kalmykov N N, Knurenko S P, Lawrence M A, Mantsch P, Medina-Tanco G A Watson A A, Mikhailov A A, Nagano M, Pierog T Warner K, Pierre Auger Collaboration, Pravdin M I, Reil K, Sakaki N, Sciutto S J, Shinozaki K Teshima M, Sinnis G, Sokolsky P, Stokes B T, TA Collaboration, Takeda M, Teshima M, Teshima M, Tinyakov P G, Véron-Cetty M P Véron P, Winn M M, Winn M M, Yao W M, Yoshida S, Zatsepin G T, Zatsepin G T   +53 more
core   +1 more source

Direction-of-Arrival Estimation Based on Sparse Recovery with Second-Order Statistics [PDF]

, 2015
Traditional direction-of-arrival (DOA) estimation techniques perform Nyquist-rate sampling of the received signals and as a result they require high storage.
Chen, H., Fan, R., Wan, Q., Wen, F.
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Analysis and optimization of an omnidirectional direction-finding system [PDF]

, 1970
System determines the direction of arrival of an electromagnetic wave with the direction information in a readily usable form.
Beste, J. M., Graf, E. R.
core   +1 more source

Power-Based Direction-of-Arrival Estimation Using a Single Multi-Mode Antenna

, 2017
Phased antenna arrays are widely used for direction-of-arrival (DoA) estimation. For low-cost applications, signal power or received signal strength indicator (RSSI) based approaches can be an alternative. However, they usually require multiple antennas,
Dammann, Armin, Jost, Thomas, Pöhlmann, Robert, Zhang, Siwei   +3 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source