Results 51 to 60 of about 2,673,893 (279)

On the Rodrigues Formula Solution of the Hypergeometric-Type Differential Equation [PDF]

open access: yes, 2013
In this paper, we present a new systematic approach to the solution of the hypergeometric-like differential equation and its associated equation. The method produces, tout court, the general solution of these equations in the form of a combination of a ...
Robin, William
core   +1 more source

A DIRECT LYAPUNOV METHOD FOR DELAY DIFFERENTIAL EQUATIONS [PDF]

open access: yesInternational Journal of Pure and Apllied Mathematics, 2015
This presentation is devoted to well-known tools of stability theory: Lyapunov functions and functionals. The development of delay equation theory through time based on some results of Russian mathematicians is discussed. In particular, there are two different approaches: one could measure the distance between points in a finite dimension space or ...
openaire   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Solution of TheHypergeometrical Differential Equation and SomeDifferentialEquation Related IT [PDF]

open access: yes, 2017
In this research I discussed the hypergeometric Differential Equation and its various properties and how the second order named Ordinary Differential Equations can be obtained from it, such as: Bessel and Legendre Differential ...
Ahmed Mohamed Ishag Ahmed
core  

The Multiple Sclerosis Severity Allele rs10191329A and Cognitive Function: A UK Biobank Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The genome‐wide association study of Multiple Sclerosis severity linked the genetic variant rs10191329A to long‐term disability and implicated brain resilience as a determinant of outcome. We hypothesised that rs10191329A might influence cognition in other neurological diseases and healthy controls.
Ioanna Zimianiti   +5 more
wiley   +1 more source

Mathematical model describing erythrocyte sedimentation rate. Implications for blood viscosity changes in traumatic shock and crush syndrome

open access: yesBioMedical Engineering OnLine, 2005
Background The erythrocyte sedimentation rate (ESR) is a simple and inexpensive laboratory test, which is widespread in clinical practice, for assessing the inflammatory or acute response.
Shevchuk Nikolai A   +2 more
doaj   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen   +6 more
wiley   +1 more source

Dynamic Performance of Asymmetric Herringbone-Groove Journal Bearings Lubricated with Gallium-Based Liquid Metal

open access: yesLubricants
To address lubricant film oscillation and rotor whirl instability caused by unreasonable bearing configurations in X-ray tubes, this study systematically investigated the dynamic performance of asymmetrically distributed herringbone-groove journal ...
Yubin Zhang   +5 more
doaj   +1 more source

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