Results 91 to 100 of about 351,527 (346)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The European technical report on aquatic effect-based monitoring tools under the water framework directive

open access: yesEnvironmental Sciences Europe, 2015
The Water Framework Directive (WFD), 2000/60/EC, requires an integrated approach to the monitoring and assessment of the quality of surface water bodies.
A. Wernersson   +46 more
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Nekaj težav pri hidravličnih analizah poplavnih tokov v zvezi z geodetskimi podlagami ; Some problems using geodetic background in hydraulic analyses of floods [PDF]

open access: yesGeodetski Vestnik, 2012
V prispevku je na kratko obravnavana problematika človekovega poseganja v vodni prostor, zlasti na potencialna poplavna območja, opisana so tudi načela umeščanja infrastrukture in poselitve v vodni prostor, določena v Direktivi o oceni in obvladovanju ...
Matija Bogdan Marinček
doaj  

ON THE ISSUE OF THE OFFSHORE AREAS

open access: yesVestnik MGIMO-Universiteta, 2013
Research issue raised in this paper is the most pressing at the moment because of international campaign to prevent money-laundering and tax evasion. From the solution to the problems that will be discussed here may depend the degree of how strong the ...
E. B. Aliyev
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

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