Results 151 to 160 of about 336,346 (356)
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
Directive Effects in the Bromination of Bicyclic Phenols. Relevance for the Mills-Nixon Effect. [PDF]
, 1971 Jonas Nilsson +5 more
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Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
wiley +1 more source
The style of EU directives and the discourse of expert rationality
Stylistyka, 2019 This article is devoted to the notion of expert rationality, understood as one of the central epistemic regimes of the discourse of the European Union.
Katarzyna Molek-Kozakowska
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Relationship of transducer apertures and separation distances to the directivity patterns in the nearfield region [PDF]
, 1974 E. E. Mikeska, C. M. McKinney
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Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
PERILAKU TINDAK TUTUR USTAD DALAM PENGAJIAN: KAJIAN SOSIOPRAGMATIK DENGAN PENDEKATAN BILINGUAL
Jurnal Penelitian Humaniora, 2013 In general, the purpose of this study is to describe the illocutionary speech act of chap- lain using bilingual approach. This is a qualitative research. The data are in the form of speech collected from recordings of cleric K.H.
Rini Indah Sulistyowati +2 more
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