Results 151 to 160 of about 865,492 (315)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
EU Services Directive - Analysis of Requirements [PDF]
The IT implementation of the EU’s Services Directive contributes to the goal of creating the most competitive and dynamic knowledge-based economic region in the world by the year 2009.
Catalin Ionut SILVESTRU +3 more
core
Directional syncretism without directional rules
MorphologyAbstract Certain patterns of directional syncretism, in particular bidirectional syncretism, have been argued to necessitate the power of directional rules that create a form dependency between two cells in a paradigm. The existence of such patterns, divergent bidirectional syncretism in particular, has been claimed to be fatal for the ...
Hein, Johannes, Murphy, Andrew
openaire +3 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Financial collateral Arrangements under Directive 2002/47/ec of the European Parliament and of the Council of 6 June 2002 [PDF]
The aim in this article is to compare effect of financial collateral arrangements under Directive 2002/47 EC. The starting point is the definitions of these contracts provided by the Financial Collateral Directive.
Ivan, Mangatchev
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Ankara Avrupa Çalışmaları Dergisi, 2012 Yabancıların hukukî durumu ve göç konularını Avrupa Birliği Müktesebatına uygun ve sistematik bir düzenlemeye kavuşturmayı amaçlayan Yabancılar ve Uluslararası Koruma Kanunu Tasarısı, TBMM’ne sunulmuştur.
Esra Dardağan Kibar
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source