Results 81 to 90 of about 336,346 (356)
A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Making public offers in the European Union [PDF]
If a couple of decades ago, the external capital of the European corporations was obtained almost entirely by bank loans, in the present, the situation changed and the finance obtained by issuance of securities is more important.
Felicia Florentina Vasile (Epure)
doaj
Managerial Structure of Editorship: Functions and Purposes
In the article the author considers collective and personalized forms of management of the editorial staff. In the author’s opinion, in the modern editions the administrative link of the edition is subject to constant changes and searches. It all depends
M. N. Kim
doaj +1 more source
In 1986, European Directive 86/609/EEC, regulating the use of animals in research, was one of the first examples of common legislation to set standards for animal protection across the Member States of the former European Economic Community, now the ...
I. Olsson+4 more
semanticscholar +1 more source
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp+5 more
wiley +1 more source
FUNDING MECHANISMS FOR IMPLEMENTATION OF MARINE STRATEGY FRAMEWORK DIRECTIVE: EU EXPERIENCE
Over the past decade, there have been signs of improvement of the Black Sea. However, its unique water areas and coastline are still under serious threat.
S. Kniaz+3 more
doaj +1 more source
The Water Framework Directive (WFD) is arguably the most ambitious piece of European Union (EU) legislation in the field of water. The directive defines a general framework for integrated river basin management in Europe with a view to achieving “good ...
Blandine Boeuf, O. Fritsch
semanticscholar +1 more source
Brucella NyxA and NyxB dimerization enhances effector function during infection
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre+4 more
wiley +1 more source
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg+2 more
wiley +1 more source
AbstractWe introduce directed bigraphs, a bigraphical meta-model for describing computational paradigms dealing with locations and resource communications. Directed bigraphs subsume and generalize both original Milner's and Sassone-Sobociński's variants of bigraphs.
DAVIDE GROHMANN, MICULAN, Marino
openaire +3 more sources