Results 101 to 110 of about 396,234 (309)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
EU Services Directive - Analysis of Requirements [PDF]
The IT implementation of the EU’s Services Directive contributes to the goal of creating the most competitive and dynamic knowledge-based economic region in the world by the year 2009.
Catalin Ionut SILVESTRU +3 more
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The First EU Social Partner Agreement in Practice: Parental Leave in the 15 Member States. IHS Political Science Series: 2004, No. 96 [PDF]
In this paper, we analyze the impact of one specific EU social policy measure, the Parental Leave Directive. This Directive is based on the first Euro-collective agreement, concluded in November 1995 by the ETUC, UNICE and CEEP.
Falkner, Gerda., Treib, Oliver
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Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The E-Commerce Directive: first evaluations [PDF]
After describing the main elements of EU Directive 2000/31/CE on electronic commerce, the article elaborates a critical analysis of its impact on EU Member States legal orders in the aim of verifying how the objective of enhancing the functioning of the ...
Fratangelo, Pierpaolo
core +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Serialization and Verification of Medicinal Products – A Pilot Study Among Pharmacists in Bulgaria
Background. In an attempt to stop the distribution of falsified medicinal products, the EU has adopted Directive 2011/62/EU. Since 9th February 2019, each package of medicinal product must be given a unique number in combination with a mandatory ...
Nedelkov N. +7 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
La determinazione del Country of origin ed il principio del mutuo riconoscimento nel nuovo testo della direttiva sui servizi di media audiovisivi [PDF]
This work analyses the new text of the Audiovisual Media Services Directive (2010/13/EU), as revised by Directive 2018/1808/EU. It focuses on the new provisions concerning the two basic principles on which the EU act is based since the “television ...
Mastroianni, Roberto
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