Results 111 to 120 of about 1,601,243 (284)
The Primacy and Direct Effect of EU International Agreements
European Public Law, 2015 The rules on invoking EU norms before the Court of Justice and Member State courts are at the core of EU constitutional law. International agreements binding on the EU form an integral part of EU law and have primacy over inconsistent secondary EU legislation. Moreover, they also have primacy over inconsistent Member State law.
openaire +3 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Do Artists Benefit from Resale Royalties? An Economic Analysis of a New EU Directive [PDF]
According to a new European Union directive, artists, whose works are resold, are entitled to a share of the sales price. The principal aim of this initiative is to let the artists participate in the economic success of their work.
Kirstein, Roland, Schmidtchen, Dieter
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Interest Income Tax Evasion, the EU Savings Directive, and Capital Market Effects [PDF]
The Savings Directive has been celebrated as a major political break-through in coordinating taxation in Europe. Against this background, the present paper evaluates the real-world effects of this directive. The directive has left a loophole by providing
Tina Klautke, Alfons Weichenrieder
core
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
The trade-induced effects of the Services Directive and the country of origin principle [PDF]
The proposed Services Directive by the European Commission could increase intra European trade in commercial services by 30 to 60 percent. This paper analyses the welfare effects of the trade growth using an applied general equilibrium model WorldScan ...
Arjan Lejour, Henk Kox, Roland de Bruijn
core
Waste management in Slovakia and Poland as European Union member states
Serbian Journal of ManagementThe basic European Union (EU) waste legislation is regulated by European Waste Framework Directive (1975). Since then, this directive has been significantly revised and updated and all EU members are obliged to implement the EU waste legislation into ...
Bartosz Nieścior, Eleonóra Marišová
doaj +1 more source