Results 91 to 100 of about 30,845 (250)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
This work presents a C-band frequency-selective surface (FSS) transmitarray antenna (TA) design with a fixed focal distance and a shared feeding horn, in which interchangeable planar apertures can be selectively replaced to enable distinct radiation ...
Iman Hiedarpour Shahrezaei +2 more
doaj +1 more source
A High-Gain Directive Superstrate Antenna for 60- GHz Applications
-A high-gain aperture coupled antenna with superstrate structure for 60 GHz communication is proposed. Unprinted dielectric slab acts as superstrate is added above the antenna in order to increase the gain performance.
# +5 more
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Radiation Characteristics of 3D Resonant Cavity Antenna with Grid-Oscillator Integrated Inside
A three-dimensional (3D) rectangular cavity antenna with an aperture size of 80 mm × 80 mm and a length of 16 mm, integrated with a four-MESFET transistor grid-oscillator, is designed and studied experimentally.
L. A. Haralambiev, H. D. Hristov
doaj +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
High directive antenna based on metamaterial slab with zero permittivity
In the present paper, the properties of an antenna centred at a metamaterial slab with zero permittivity are investigated. It is analyzed that the antenna can achieve high directive performance.
Yan, Wei,, Shen, L., Qiu, Min,
core +1 more source

