Results 241 to 250 of about 317,142 (308)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Nitrogen Excretion, Ammonia, and Greenhouse Gases Emission in Italian Heavy Pigs: The Role of Feed in Environmental Impact Mitigation. [PDF]

Animals (Basel)
Rossi R, Buoio E, Mainardi E, Costa A.
europepmc   +1 more source

Safety evaluation of the food enzyme leucyl aminopeptidase from the non-genetically modified <i>Lichtheimia ramosa</i> strain AE-PER. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Aguilera J, Andryszkiewicz M, Cavanna D, Kovalkovičová N, Liu Y.   +17 more
europepmc   +1 more source

Health care coverage and access for displaced persons from Ukraine: Assessing the implementation of the Temporary Protection Directive across EU Member States.

Health Policy
Mauer N, Hernandez-Quevedo C, Eriksen A, Scarpetti G, van Ginneken E, Network of HSPM and country experts.   +5 more
europepmc   +1 more source

A 3-Bit Low-Profile High-Gain Transmissive Intelligent Surface for Beam Focusing and Steering Applications. [PDF]

Micromachines (Basel)
Abdulwali ZSA, Alkanhal MAS.
europepmc   +1 more source

Do Great Apes Use Iconic Gestures? [PDF]

Wiley Interdiscip Rev Cogn Sci
Perlman M.
europepmc   +1 more source

Europe in a hybrid war: health security as strategic defence. [PDF]

Eur J Public Health
Marchandise C, McKee M.
europepmc   +1 more source

A high efficiency slot array antenna with single layered gap waveguide feeding system for long-range wireless systems. [PDF]

Sci Rep
Mohammadpour M, Mohajeri F, Parizi SAR.
europepmc   +1 more source

e-Learning in Phoniatrics and Speech-Language Pathology: Exploratory Analysis of Free Access Tools in Augmentative and Alternative Communication.

JMIR Med Educ
Büchs J, Neuschaefer-Rube C.
europepmc   +1 more source