Results 201 to 210 of about 18,335 (312)

Insights from electromechanical simulations to assess omecamtiv mecarbil efficacy in heart failure

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Impact of Omecamtiv Mecarbil (OM) on in‐silico models of heart failure. A mathematical electromechanical model of human ventricular tissue is used to simulate the effects of OM in heart failure with reduced ejection fraction (HFrEF).
Maria Teresa Mora   +8 more
wiley   +1 more source

Electrodiffusion in cardiac intercalated disc nanostructures alters cell–cell action potential transmission via ephaptic coupling: A model study

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Ephaptic phenomena in a high‐resolution model of the cardiac intercalated disc. Meshed representation of a tortuous intercalated disc that was generated based on electron and super‐resolution microscopy data. Na+ channels (red) and gap junctions (green) are heterogeneously distributed, with additional regions of reduced ion ...
Ena Ivanovic   +4 more
wiley   +1 more source

Semiclassical inequalities for Dirichlet and Neumann Laplacians on convex domains

open access: yesCommunications on Pure and Applied Mathematics, Volume 79, Issue 3, Page 762-822, March 2026.
Abstract We are interested in inequalities that bound the Riesz means of the eigenvalues of the Dirichlet and Neumann Laplacians in terms of their semiclassical counterpart. We show that the classical inequalities of Berezin–Li–Yau and Kröger, valid for Riesz exponents γ≥1$\gamma \ge 1$, extend to certain values γ<1$\gamma <1$, provided the underlying ...
Rupert L. Frank, Simon Larson
wiley   +1 more source

Toward Dynamic Phase‐Field Fracture at Finite Strains

open access: yesPAMM, Volume 26, Issue 1, March 2026.
ABSTRACT We investigate the evolution of dynamic phase‐field fracture in the finite‐strain setting, extending our previous work in the small‐strain viscoelastodynamic regime. The elastodynamic equations are coupled with a dissipative damage evolution for the phase‐field variable z$z$.
Sven Tornquist   +4 more
wiley   +1 more source

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