Results 71 to 80 of about 455,221 (309)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

The global burden of cardiovascular disease attributable to high alcohol use from 1990 to 2021: an analysis for the global burden of disease study 2021

Frontiers in Public Health
BackgroundCardiovascular diseases (CVDs) are the leading global disease burden, with alcohol consumption closely linked to their occurrence. This study analyzes data from the Global Burden of Disease Study 2021 (GBD 2021) to assess the distribution and ...
Chaofeng Niu, Juwei Dong, Peiyu Zhang, Qiwen Yang, Donghua Xue, Birong Liu, Di Xiao, Rui Zhuang, Meng Li, Lijing Zhang   +9 more
doaj   +1 more source

The burden of neck pain in Brazil: estimates from the global burden of disease study 2019

BMC Musculoskeletal Disorders, 2021
Background This study analyzed neck pain estimates in Brazil and its states between 2000 and 2019, in view of the country’s lacking epidemiological data.
Lucas de Melo Castro Deligne, Maria Clara Brant Rocha, Deborah Carvalho Malta, Mohsen Naghavi, Valéria Maria de Azeredo Passos   +4 more
doaj   +1 more source

Impact of multimorbidity on disability and quality of life in the spanish older population  [PDF]

, 2015
BACKGROUND: Population aging is closely related to high prevalence of chronic conditions in developed countries. In this context, health care policies aim to increase life span cost-effectively while maintaining quality of life and functional ability ...
Ayuso Mateos, José Luis, Garin, Noe, Haro Abad, Josep Maria, Lobo, Antonio, Miret, Marta, Moneta, Maria Victoria, Olaya Guzmán, Beatriz   +6 more
core   +2 more sources

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Burden of diarrhea in the Eastern Mediterranean region, 1990-2013 : findings from the Global burden of Disease study 2013 [PDF]

, 2016
Diarrheal diseases (DD) are leading causes of disease burden and death and disability, especially in children in low-income settings. DD can also impact a child’s potential livelihood through stunted physical growth, cognitive impairment, and other ...
HASH(0x55f513cfb6d8), Uthman, Olalekan A.   +1 more
core   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Using linked data to calculate summary measures of population health: Health-adjusted life expectancy of people with Diabetes Mellitus [PDF]

, 2004
Objectives To estimate the health-adjusted life expectancy (HALE) from diabetes mellitus (DM) using a population health survey linked to a population-based DM registry. Methods
Manuel, Douglas G, Schultz, Susan E
core   +3 more sources

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

Disability-adjusted life years (DALYs) for transport injuries

ISEE Conference Abstracts, 2013
Background: Health impact assessment (HIA) studies are increasingly combining adverse health effects of different stressors. Injuries, caused by transport accidents, is one such stressor.
Marko Tainio, Grzegorz Teresinski, Audrey de Nazelle, Mark J Nieuwenhuijsen   +3 more
openaire   +2 more sources