Results 101 to 110 of about 2,492,272 (348)
Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin +2 more
wiley +1 more source
Background Mental disorders account for a significant proportion of the world’s disease burden and are more significant among females than males. However, most global mental health research is sex neutral, including in the Kingdom of Saudi Arabia.
Yasmin A. Altwaijri +7 more
doaj +1 more source
Maximizing Productivity: Accomodations for Emergency Preparedness [PDF]
[Excerpt] Emergency planning is just as critical for the workplace as it is for the home. In recent years, the nation, particularly the federal government, has re-evaluated its approach to emergency preparedness and response.
Office of Disability Employment Policy
core +1 more source
“I’d Rather Be Dead Than Disabled”—The Ableist Conflation and the Meanings of Disability [PDF]
Despite being assailed for decades by disability activists and disability studies scholars spanning the humanities and social sciences, the medical model of disability—which conceptualizes disability as an individual tragedy or misfortune due to genetic ...
Reynolds, Joel Michael
core +1 more source
ABSTRACT Pathogenic variants in KIF1C cause Spastic Paraplegia 58 (SPG58), typically presenting with cerebellar ataxia and spastic paraparesis. We report two unrelated patients with spastic paraparesis, cerebellar ataxia, and tremor. Whole‐exome sequence analysis identified novel homozygous variants in the motor domain of KIF1C (NM_006612.6): c.921G>A (
Akihiko Mitsutake +12 more
wiley +1 more source
The Job Accommodation Process: Steps To Collaborative Solutions [PDF]
[Excerpt] A reasonable accommodation is any change in the work environment or in the way things are usually done that enables an individual with a disability to participate in the application process, to perform the essential functions (or fundamental ...
Office of Disability Employment Policy
core +1 more source
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Entrepreneurship: A Flexible Route To Economic Independence For People With DIsabilities [PDF]
[Excerpt] In recent years, changes in the global marketplace have significantly altered the character of the nation’s workforce. Trends such as downsizing, increased use of contingent, contract and temporary employees, and new ways of delivering goods ...
Office of Disability Employment Policy
core +1 more source
Insomnia and long sleep duration are risk factors for later work disability. The Hordaland Health Study [PDF]
Børge Sivertsen +6 more
openalex +1 more source
Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen +11 more
wiley +1 more source

