Results 121 to 130 of about 458,686 (310)

Calculating disability-adjusted life years to quantify burden of disease

International Journal of Public Health, 2014
The disability-adjusted life year or DALY is a summary measure of public health widely used to quantify burden of disease. In the DALY philosophy, every person is born with a certain number of life years potentially lived in optimal health. People may lose these healthy life years through living with illness and/or through dying before a reference life
Devleesschauwer, Brecht, Havelaar, Arie H, Maertens de Noordhout, Charline, Haagsma, Juanita A, Praet, Nicolas, Dorny, Pierre, Duchateau, Luc, Torgerson, Paul R, Van Oyen, Herman, Speybroeck, Niko   +9 more
openaire   +6 more sources

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source

Calculating disability-adjusted-life-years lost (DALYs) in discrete-time [PDF]

Cost Effectiveness and Resource Allocation, 2013
Disability-adjusted-life-years lost (DALYs) is a common outcome metric for cost-effectiveness analyses, and the equations used for such calculations have been presented previously by Fox-Rushby and Hanson (see, e.g., "Health Policy and Planning 16:326-331, 2001").
openaire   +2 more sources

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Global, regional, and national burdens of pertussis among adults: a systematic analysis of age-specific trends using Global Burden of Diseases 2021 data

Infectious Diseases of Poverty
Background Despite the high coverage of childhood vaccination, pertussis remains a significant global health challenge, with increasing adult cases attributed to waning immunity and enhanced diagnostic capability.
Kangguo Li, Jiadong Wu, Ruixin Zhang, Yulun Xie, Zecheng Zhou, Qi Yin, Qi Chen, Jia Rui, Xuhua Guan, Zeyu Zhao, Tianmu Chen   +10 more
doaj   +1 more source

The burden of disease and injury in Australia

, 1999
This report provides an overview of results from the Australian Burden of Disease and Injury Study undertaken by the AIHW during 1998 and 1999. The Study uses the methods developed for the Global Burden of Disease Study, adapted to the Australian context
Mathers, Colin, Stevenson, Chris, Vos, Theo   +2 more
core  

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Are Nursing Students’ Thesis Topics in Accordance with Burden of Diseases as Disability Adjusted Life Years in Iran? [PDF]

, 2006
Introduction: Research is the basis of nursing and should be in accordance with society’s health needs. The purpose of this study was to determine whether the master theses’ subjects in nursing conform to the burden of diseases as Disability Adjusted ...
Aein, Fereshteh, Ahmadi, Fazlollah, Heravi Karimooi, Majideh, Tootoonchi, Mina   +3 more
core  

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Deriving disability weights for the Netherlands: findings from the Dutch disability weights measurement study

Population Health Metrics
Background The aims of this study were to establish national disability weights based on the health state preferences of a Dutch general population sample, examine the relation between results and respondent’s characteristics, and compare disability ...
Juanita A. Haagsma, Periklis Charalampous   +1 more
doaj   +1 more source