Results 241 to 250 of about 458,686 (310)

Predominance of Ferroptotic Cell Death Mechanisms in Substantia Nigra Neurodegeneration in Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective The extent of neuronal loss in Parkinson's disease (PD) and the pathogenic processes underlying neuronal dysfunction and loss remain poorly understood. Here, we analyzed the expression of key molecules representing different cell death signaling pathways and their association with Lewy pathology, dopaminergic (DA) neuron loss and stage of PD ...
Yue Jing Heng   +3 more
wiley   +1 more source

Analysis of the Global Burden of Disease study highlights the global, regional, and national trends of chronic kidney disease epidemiology from 1990 to 2016 [PDF]

open access: yes, 2018
Al-Aly, Ziyad   +9 more
core   +1 more source

Hyperreflective Foci in the Inner Nuclear Layer: Proof‐of‐Concept for an Optical Coherence Tomography Derived Microglia‐Related Marker in Multiple Sclerosis

open access: yesAnnals of Neurology, EarlyView.
The role of microglia has emerged as a critical driver of disease progression in multiple sclerosis (MS), but we lack broadly applicable monitoring tools. Here, we investigated whether hyperreflective foci (HRF), as detected by optical coherence tomography (OCT) within the inner nuclear layer (INL) of the retina, can be used as a marker for microglial ...
Jonathan A. Gernert   +13 more
wiley   +1 more source

Use of Machine Learning to Identify Markers of Risk for Fragile X‐Associated Tremor/Ataxia Syndrome: A Preliminary Analysis

open access: yesAnnals of Neurology, EarlyView.
Objective The objective of this study was to examine whether machine learning has the capacity to prospectively identify and predict the emergence of Fragile X‐associated tremor/ataxia syndrome (FXTAS) among male fragile X premutation carriers (PCs). Methods We explored neuropsychological and motor evaluation metrics, brain magnetic resonance imaging ...
Chitrabhanu Gupta   +10 more
wiley   +1 more source

Inter‐microscope comparability of dental microwear texture data obtained from different optical profilometers: Part II Deriving instrument‐specific correction equations for meta‐analyses using published data

open access: yesThe Anatomical Record, EarlyView.
Abstract Dental microwear texture analysis (DMTA) has emerged as a valuable method for investigating the feeding ecology of vertebrates. Over the past decade, three‐dimensional topographic data from microscopic regions of tooth surfaces have been collected, and surface texture parameters have been published for both extant and fossil species.
Mugino O. Kubo   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy