Results 71 to 80 of about 14,755,209 (285)

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Beyond disability-adjusted life years (DALYs) : developing indicators to assess the impact of public health interventions on the lives of people with disabilities [PDF]

This paper proposes two measures for assessing the impact of interventions on the lives of disabled people, the Activity Limitation Score (ALS) and the Participation restriction Score (PRS).
Mont, Daniel, Loeb, Mitchell
core  

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Burns: Epidemiology and Distribution Pattern in Karachi – A One-Year Survey

Pakistan Journal of Medicine and Dentistry, 2019
Background: Burns are associated with morbidity and mortality and have greatly affected mankind. They form the fourth most type of trauma encountered worldwide, preceded by traffic accidents and homicidal violence.
Qudsia Hassan, Mohd Ikram Ali, Farhat Mirza   +2 more
doaj  

Paramagnetic Rim Lesions and Choroid Plexus Volume at Diagnosis Are Associated With Cognitive Progression Independent of Relapse and MRI Activity in Early Relapsing–Remitting Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) and choroid plexus (CP) enlargement reflect smoldering inflammation in multiple sclerosis. Their role in cognitive progression remains unexplored. Eighty‐seven early relapsing–remitting MS patients were enrolled at diagnosis and followed longitudinally.
Stefano Ziccardi, Damiano Marastoni, Agnese Tamanti, Pietro Biasi, Valentina Visani, Annalisa Colombi, Tom A. Fuchs, Monica Sicchieri, Chiara Eccher, Francesco Guarnaccia, Milena Calderone, Valentina Camera, Francesca Benedetta Pizzini, Roberta Magliozzi, Marco Castellaro, Massimiliano Calabrese   +15 more
wiley   +1 more source

The persistence of very low correlations between NIH research funding and disease burdens

Public Health in Practice
Objectives: The degree to which the allocation of disease-specific research funding by the NIH is proportional to disease burden is an important question.
Ashley J.R. Carter, Milena Gevorkian
doaj   +1 more source

Estimation of Burden of Cystic Echinococcosis in Iran Using Disability Adjusted Life Years (DALYs) in 2018

Iranian Journal of Public Health, 2021
Background: Human hydatidosis as a public concern has increased in a number of countries that have reduced control programs for the disease due to lack of resources or policies.
Fateme Parandin, Fatemeh Heydarpour, Mehdi Mohebali, Ahmad Ali Hanafi-Bojd, Ali Akbari Sari, Mohamad Zeynali, Ahad Alizadeh, Naser Nazari, Farzad Kaveh, Mohammad Bagher Rokni   +9 more
doaj  

Disability-adjusted life years lost due to diabetes in France, Italy, Germany, Spain, and the United Kingdom: a burden of illness study

, 2015
Josep Darbà,1 Lisette Kaskens,2 Bruno Detournay,3 Werner Kern,4 Antonio Nicolucci,5 Domingo Orozco-Beltrán,6 Antonio Ramírez de Arellano71Department of Economics, University of Barcelona, Barcelona, Spain; 2Department of Health ...
Ramírez de Arellano A, Detournay B, Darbà J, Nicolucci A, Orozco-Beltrán D, Kaskens L, Kern W   +6 more
core  

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi, Sola Al Ghazal, Salem Hannoun, Medhat A. Siddik, Nour M. Najjar, Jim Dagher, Joseph Abboud, Myriam G. Semaan, Samia J. Khoury   +8 more
wiley   +1 more source

Disability-adjusted Life Years for Acute Bronchiolitis [PDF]

, 2020
BACKGROUND: The burden of disease generated by acute bronchiolitis (AB) in infants is unknown in developing countries. Evidence on the disease burden is important for decision-making processes within the health sector. The objective of the present study is to determine the Disability-Adjusted Life Years in a middle-income country METHODS: DALYs were ...
openaire   +1 more source