Results 71 to 80 of about 1,141,114 (246)

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

open access: yesAdvanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li   +8 more
wiley   +1 more source

Disability Culture and the ADA

open access: yesDisability Studies Quarterly, 2015
This article begins with a personal, pre-Americans with Disabilities Act (ADA) story of employment discrimination and how from it I became involved with the Disability Rights Movement.
Steven E. Brown
doaj   +1 more source

NSD2 Coordinates the Neurogenic‐to‐Gliogenic Transition via H3K36me2‐Dependent Activation of the EGFR‐ERK Pathway

open access: yesAdvanced Science, EarlyView.
NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen   +7 more
wiley   +1 more source

Discrimination Among Disabled Adults in the United States: Findings from the 2022 National Survey on Health and Disability

open access: yesDisabilities
Disabled people face discrimination in healthcare settings, yet the compounding effects of intersectional identities remain underexplored. This project examines how different types of discrimination affect healthcare access and outcomes.
Abby Mulcahy   +8 more
doaj   +1 more source

Representations of Disability in the Old Testament and Their Implication for the Nexus between Poverty and Disability

open access: yesOld Testament Essays, 2023
Historically, disability has been part of the human condition such that persons with disabilities have existed in virtually all societies from ancient to modern times.
Makomborero Allen Bowa
doaj  

Bending‐Stable Pressure Sensor Based on Natural Wood Nanofibers for Ultra‐Low Detection Limit

open access: yesAdvanced Science, EarlyView.
A wood nanofiber‐based flexible pressure sensor with intrinsic bending‐stable performance is developed through a porous electrospun architecture and interdigital electrode design. The device exhibits an ultra‐low detection limit and stable operation under deformation for physiological monitoring and spatial sensing, providing a sustainable strategy for
Xu Zeng   +7 more
wiley   +1 more source

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi   +7 more
wiley   +1 more source

Disability discrimination in emergencies: The return of Taurek?

open access: yesEthic@: an International Journal for Moral Philosophy
John Taurek famously advocates an unpopular view in ethics: when deciding whom to rescue, the numbers don’t count. We should instead give everyone the same chance of surviving by choosing at random. Surprisingly little engagement has taken place between
Ben Davies
doaj   +1 more source

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