Results 81 to 90 of about 1,207,236 (288)

Disability, Discrimination, and Mental Health during the COVID-19 Pandemic: A Stress Process Model. [PDF]

Soc Ment Health, 2022
Brown RL, Ciciurkaite G.
europepmc   +1 more source

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

Advanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang, Chang Liu, Yuneng Zhou, Kaichen Zhao, Muyang Li, Bingcheng Cai, Ying Wang, Zhiyuan Yuan, Zhaoxin Liu, Zilong Yuan, Yao Xiao, Peiyang Zhou, Ke Shui, Wendai Bao, Min Zhang, Jun Qin, Jun Chen, Xin Yang, Zhiqiang Dong   +18 more
wiley   +1 more source

Policies to change attitudes to people with disabilities

Scandinavian Journal of Disability Research, 2017
Negative attitudes are a major barrier to the equality of people with disabilities. Governments and other organizations have implemented numerous programmes to change attitudes towards people with disabilities.
Karen R. Fisher, Christiane Purcal
doaj   +1 more source

Ever-changing but always constant: "Waves" of disability discrimination during the COVID-19 pandemic in the United States. [PDF]

Disabil Health J, 2022
Lund EM, Ayers KB.
europepmc   +1 more source

Neuron‐Derived Vesicular circMagi1 Restrains Vascular Repair After Ischemic Stroke by Promoting TRIM65‐Mediated ANXA2 Degradation

Advanced Science, EarlyView.
After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi, Qun Liu, Baohua Zou, Wenyuan Wang, Xinlong Qiao, Lin Gao, Chaoxu Miao, Ningning Huang, Shuqing Tang, Rui Guo, Changqing Zeng, Ce Jia, Yuanchao Xue, Xuejun Guo, Jianjun Chen, Huiwen Wang, Guangju Ji   +16 more
wiley   +1 more source

Disability discrimination in insurance [PDF]

De Jure, 2018
Diskriminasie in die finansiële sektore soos versekering word nie alledaags onder die loep geneem nie. Die een industrie waarin daar daagliks teen persone gediskrimineer word, is versekering. Versekeringsmaatskappye groepeer versekerdes in verskillende risikogroepe volgens hulle risiko-profiele.
openaire   +2 more sources

JOB DISCRIMINATION AGAINST INDIVIDUALS WITH DISABILITIES

Humanities and Social Sciences
The purpose of this study is to identify the relationship between holding a disability certificate and job discrimination. The motivation for conducting this research is to identify a research gap relating to the insufficient recognition of the issue of ...
Elżbieta STOLARSKA-SZELĄG, Katarzyna KRÓL   +1 more
doaj   +1 more source

Persistent Zn2+ Influx‐Mediated Deacetylation of ANXA2 Regulates the “Zn2+‐Autophagic Flux” and Alleviates Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Zinc transporter SLC39A14 sustains intracellular Zn2+ levels to activate SIRT3‑dependent ANXA2 deacetylation at K302. This modification weakens ANXA2‑mTOR binding and releases autophagic‑flux suppression in nucleus pulposus cells. Dysregulated Zn2+ homeostasis disrupts this axis to drive intervertebral disc degeneration.
Yuxin Jin, Yongcheng Chen, Yihao Xie, Dongyang Hu, Longhui Gong, Zhihua Chen, Linjie Chen, Minhao Gao, Qizhu Chen, Morgan Jones, Hui Wang, Xiuling You, Kenny Yat Hong Kwan, Shoutao Weng, Taidong Lyu, Xiang Chen, Yuxiao Zhu, Yusheng Wang, Bin Li, Xiangyang Wang, Xiaofeng Jia, Kailiang Zhou, Ouqiang Wu, Aimin Wu   +23 more
wiley   +1 more source

The legality of weight discrimination in Canada: an environmental scan of case law and the limits of Canadian legislation

International Journal for Equity in Health
Weight stigma negatively impacts people with higher weights across the lifespan as well as social contexts and can lead to weight discrimination. As weight is not a protected identity in Canadian human rights legislation, it is important to better ...
Sarah Nutter, Rachel Waugh, Erin McEachran, Ashley Toor, Jacob Shelley, Angela S. Alberga, Mary Forhan, Sara FL Kirk, Taniya S. Nagpal, Ian Patton, Ximena Ramos Salas, Shelly Russell-Mayhew   +11 more
doaj   +1 more source

"Just How Much Diversity Will the Law Permit?": The Americans with Disabilities Act, Diversity and Disability in Higher Education

Disability Studies Quarterly, 2015
Civil rights laws including the Civil Rights Act of 1964, Title IX of 1972, Section 504 of the Rehabilitation Act of 1973 and the Americans with Disabilities Act of 1990 worked to protect classes and individuals for whom discrimination had been ...
Lauren Shallish
doaj   +1 more source