Results 51 to 60 of about 977,774 (302)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Evaluation of health impacts of a disability-inclusive graduation programme among ultra-poor people with disabilities in Uganda: secondary analysis of a cluster randomized trialResearch in context

EClinicalMedicine
Summary: Background: People with disabilities experience significant health inequalities and barriers to healthcare access globally. While poverty alleviation interventions show promise for improving health outcomes, evidence specifically for people ...
Shanquan Chen, Lena Morgon Banks, Elijah Kipchumba, Calum Davey, Munshi Sulaiman, Hannah Kuper   +5 more
doaj   +1 more source

Patient-Reported Disability Measures Do Not Correlate with Electrodiagnostic Severity in Carpal Tunnel Syndrome. [PDF]

, 2017
BACKGROUND: Electrophysiologic studies including electromyography and nerve conduction studies play a role in the evaluation of carpal tunnel syndrome (CTS), despite evidence that these studies do not correlate with CTS-specific symptom scores.
Atroshi, Bakhsh, Bessette, Chan, Changulani, Cohen, Das De, de la Llave-Rincón, de-la-Llave-Rincon, Graham, Itsubo, Jablecki, Jordan, Kimura, Kronlage, Levine, Makanji, Niekel, Nunez, Robinson, Sandin, Sucher, Ware, Watson, Werner, Wilder-Smith   +25 more
core   +2 more sources

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Medical expertise in non-contentious proceedings [PDF]

Vojnosanitetski Pregled, 2018
nema
Trgovčević-Prokić Milena, Počuča Milan, Šarkić Nebojša   +2 more
doaj   +1 more source

Perceived disability from hearing and voice changes in the elderly [PDF]

, 2014
Aim: Dysphonia and hearing loss are underestimated conditions in the elderly, despite their significant prevalence (18% and 50%, respectively) and their sociopsychological implications.
BARBARA, Maurizio, FILIPPI, CHIARA, MONINI, Simonetta, Rossella Baldini   +3 more
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Prevalence of disability in Iranian older adults in Tehran, Iran: A population-based study [PDF]

Journal of Health and Social Sciences, 2016
Introduction: The increase in the prevalence of disability has serious consequences for elders, their families, and the society in general. The effects of disability on an aging population’s health and welfare are important issues in gerontological ...
Vahid Rashedi, Mohsen Asadi-Lari, Mahshid Foroughan, Ahmad Delbari, Reza Fadayevatan   +4 more
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Achieving Quality: Consumer Involvement in Quality Evaluation of Services [PDF]

, 2003
[Excerpt] The aim of this paper is to raise awareness of the fact that changes in the approach towards the “clients” or “consumers” of services for people with intellectual disability do have an important impact on the way the quality evaluation systems ...
Inclusion Europe
core   +1 more source