Results 31 to 40 of about 1,654,065 (252)

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

The Sexual Politics of Disability, Twenty Years On

open access: yesScandinavian Journal of Disability Research, 2018
This paper follows up on qualitative interviews conducted with British disabled people in 1994–6, exploring how people’s lives and relationships have changed over twenty years (n = 8).
Tom Shakespeare, Sarah Richardson
doaj   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

Disability, Climate Change, and Environmental Violence: The Politics of Invisibility and the Horizon of Hope

open access: yesDisability Studies Quarterly, 2020
This article brings disability theory and activism into conversation with environmental justice, a conversation that has often been stymied by a fundamental difference in approaching disability.
Julia Watts Belser
doaj   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch   +5 more
wiley   +1 more source

The uncanny memory of Nazi euthanasia, the Risiera di San Sabba and the foibe

open access: yesIncontri: Rivista Europea di Studi Italiani, 2015
Review of: Susanne Knittel, The Historical Uncanny: Disability, Ethnicity, and the Politics of Holocaust Memory, New York, Fordham University Press, 2015, XII + 350 p., ISBN: 9780823262786, $55 ...
Emiliano Perra
doaj   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Of Non-Mice and Non-Men: Against Essentialism in Joshua Ferris's The Unnamed

open access: yesDisability Studies Quarterly, 2020
Noticing the recent trend in disability studies to entertain essentialism in an attempt to capture the efficacy of identity politics, this essay articulates the reductive implications of doing so.
Nathan D. Frank
doaj   +1 more source

Clinician and Patient Factors Associated With Long‐Term Glucocorticoid Use in People With Rheumatoid Arthritis Receiving Advanced Therapies

open access: yesArthritis Care &Research, EarlyView.
Objective Despite guideline recommendations, long‐term glucocorticoid (GC) use is common in rheumatoid arthritis (RA). We conducted a clinician survey nested within a large registry to identify patient and clinician factors associated with GC use. Methods Clinicians contributing patients to the CorEvitas Rheumatoid Arthritis Registry were surveyed ...
Michael D. George   +7 more
wiley   +1 more source

Selective Abortion as Moral Failure? Revaluation of the Feminist Case for Reproductive Rights in a Disability Context

open access: yesDisability Studies Quarterly, 2016
Of feminism and disability theory's many overlapping concerns, few have received as much attention as prenatal genetic diagnosis and selective abortion. While the attention to how genetic selection reinforces disability stigma is important, much of this ...
Claire McKinney
doaj   +1 more source

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