Results 61 to 70 of about 1,654,065 (252)
What is there to see in others? How to avoid sorters trends that lead us to include a fixed or negative identity; a fortiori when it is a disability? How to articulate, from an ethical point of view, the necessary diagnostic of others’ suffering with ...
Fred Poché
doaj +1 more source
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu +13 more
wiley +1 more source
Other title: Kansas Department for Aging and Disability Services Update; Other title: Update
application/pdf; "August 5, 2016."; "Reporting Date 06/30/2016."; Presentation before the Kansas Legislature, Robert G. Bethell Joint Committee on Home and Community Based Services and KanCare Oversight, presented by the Kansas ...
Kansas. Department for Aging and Disability Services.
core +1 more source
Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu +7 more
wiley +1 more source
"Effective July 1, 2015.""Instructions for CARE Level II Preadmission Screening for Intellectual/Developmental Disability and Other Related ...
Kansas. Department for Aging and Disability Services. CARE Program.
core
Other title: Kansas Department for Aging and Disability Services Update; Other title: Update
"April 19, 2017."Presentation before the Kansas Legislature, Robert G. Bethell Joint Committee on Home and Community Based Services and KanCare Oversight, presented by the Kansas Department for Aging and Disability Services.Presentation giving statistics
Kansas. Department for Aging and Disability Services.
core +1 more source
The Role of the Evaluation in the Theoretical Focuses on the Social Politics: the Case of Disability
The social politics constitute a space of interesting diverse and contradictory analysis inside the different social contexts. Their reach should guide us toward the different sectors of the society in the search of its social well-being.
MSc. Osmanys Soler-Nariño +1 more
doaj
Chinese Special Needs Adoption, Demand, and the Global Politics of Disability
This article explores three related phenomena: first, the abandonment and institutionalization of children with disabilities in China that increased disproportionately in the 2000s; second, the important relationships between such abandonments, culture ...
Erin Raffety
doaj +1 more source
MG1@NM‐Px serves as a microglia‐targeted STING‐degrading nanoplatform for subarachnoid hemorrhage. Following systemic administration, it crosses the blood–brain barrier and accumulates in activated microglia. STP1‐mediated STING ubiquitination and degradation suppress MAPK/inflammasome signaling, GSDME‐mediated pyroptosis, and IL‐1β release, revealing ...
Ruotian Zhang +13 more
wiley +1 more source
AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li +8 more
wiley +1 more source

