Results 101 to 110 of about 367,868 (311)
Persons with disabilities in light of the National Census of Population and Housing 2011 : selected aspects [PDF]
, 2014 This article aims to present the most important critical information gained about disabled persons in the National Census of Population and Housing 2011, referring not only to the number, types of disability, but the main socio-demographic ...
Slany, Krystyna
core
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models
Advanced Science, EarlyView.His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li +13 more
wiley +1 more source
User Driven Innovation: Incorporating Disabled Lead Users in Early Phase Product Development [PDF]
, 2014 How can disabled non-designers play a leading role in product development? As part of early phase product ideation, designers often rely on methods (Pahl & Beitz, 1996, Chapter 4).
Conradie, Peter
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Advanced Science, EarlyView.ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao +12 more
wiley +1 more source
Disability in the Netherlands: Another Dutch disease? [PDF]
The Netherlands is well known for its high employment growth and corresponding low unemployment rate. At various occasions the so-called Dutch miracle has been applauded, together with the underlying ‘Polder model’.
Muysken,Joan, Rutten,Tim
core +1 more source
State Estimates of Employment Rates for Persons with Disabilities: Report Summary [PDF]
, 2001 Statistics on the states’ employment rates for persons with disabilities relative to their non-disabled peers may be of assistance to providers of employment services for persons with disabilities.
Houtenville, Andrew J.
core +1 more source
Advanced Science, EarlyView.When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley +1 more source
Hearing loss prevalence and burden of disease in China: Findings from provincial-level analysis
Chinese Medical Journal. Background:. Without timely and effective rehabilitation, hearing loss may profoundly affect human life quality. China has a large population of hearing-impaired individuals, which imposes a heavy health burden on society. Moreover, this population is
Yu Wang +15 more
doaj +1 more source
Attitudes and empathy of youth towards physically disabled persons. [PDF]
Heliyon, 2021 Sharma N, Pratap Yadav V, Sharma A.
europepmc +1 more source