Results 101 to 110 of about 1,026,916 (276)
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
La política deliberativa y las “virtudes” del procedimiento. Un análisis crítico del procedimentalismo de Habermas [PDF]
Revista Enfoques, 2013 Habermas aims to overcome the debate between liberalism and republicanism by integrating elements from both traditions and trying to outline a procedural understanding of democracy.
Vicente Montenegro Bralic
doaj
Members of different social groups often hold widely divergent public beliefs regarding the nature of the world in which they live. We develop a model that can accommodate such public disagreement, and use it to explore questions concerning the ...
Muhamet Yildiz, Rajiv Sethi
core
Group disagreement: a belief aggregation perspective [PDF]
, 2019 The debate on the epistemology of disagreement has so far focused almost exclusively on cases of disagreement between individual persons. Yet, many social epistemologists agree that at least certain kinds of groups are equally capable of having beliefs ...
Skipper, Mattias +1 more
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Religious Disagreement in Analytic Theology
St Andrews Encyclopaedia of TheologyReligious disagreement means holding incompatible views of the truth or of the plausibility of some position that is religiously relevant. It is well known that many religious and non-religious worldviews make apparently incompatible claims about ...
Olli-Pekka Vainio
doaj
Relative Disagreement-Point Monotonicity of Bargaining Solutions [PDF]
Prominent bargaining solutions are disagreement-point monotonic. These solutions’ disagreement-point monotonicity ranking, on the other hand, is impossible to establish.
Nejat Anbarci
core
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source