Results 51 to 60 of about 1,026,916 (276)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Religious Diversity and Disagreement [PDF]
, 2019 Epistemologists have shown increased interest in the epistemic significance of disagreement, and in particular, in whether there is a rational requirement concerning belief revision in the face of peer disagreement.
Benton, Matthew A.
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Kavramsal Tutarlılığın Önemi Bağlamında Gazzâlî’nin Müşterek Lafızlara Yaklaşımı
Diyanet İlmi DergiTürkçe çok anlamlılık manasına gelen “iştirâk-ı lafzî” veya “müşterek lafız”, telaffuzu aynı, anlamı farklı olan kelimeler için kullanılan bir kavramdır.
Fehmi Soğukoğlu
doaj +1 more source
The Significance of Ethical Disagreement for Theories of Ethical Thought and Talk [PDF]
, 2017 This chapter has two sections, each focusing on a distinct way in which ethical disagreement and variations in ethical judgment matter for theories of ethical thought and talk.
Björnsson, Gunnar
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Kur’an’da Okuyucudan Kaynaklı Çelişki Algısı ve Çözüm Yöntemleri
Kocaeli İlahiyat DergisiBu makale, ulûmu’l-Kur’ân literatüründe Kur’an âyetlerinin anlaşılması sırasında ortaya çıkan anlam farklılıklarını ifade eden “ihtilaf” konusunu ele almakta ve bu çerçevede literatürde sıklıkla zikredilen “teâruz”, “tenâkuz” ve “işkâl” gibi kavramların ...
Muhammet İkbal Çalış
doaj +1 more source
Interpreting the Situation of Political Disagreement: Rancière and Habermas
Journal of French and Francophone Philosophy, 2019 Although Jacques Rancière and Jürgen Habermas share several important commitments, they interpret various core concepts differently, viewing politics, democracy, communication, and disagreement in conflicting ways.
Seth Mayer
doaj +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Relativism, Faultlessness, and the Epistemology of Disagreement [PDF]
, 2018 : Recent years have witnessed a revival of interest in relativism. Proponents have defended various accounts that seek to model the truth-conditions of certain propositions along the lines of standard possible world semantics.
Dugas, Micah
core