Results 21 to 30 of about 33,830 (238)
Disappointing article, not disappointing biotech [PDF]
BMJ, 2005 EDITOR—Joppi et al's critique and not biotech itself is disappointing.1 The authors classified most of the biotech drugs (24/61) as “copycat or me too products”—pejorative terms intended to cast prejudicial doubt on a drug's value. I am familiar with one of the drugs on the copycat list, teriparatide (rhPTH1-34, Forteo, Eli Lilly), a treatment for ...
openaire +1 more source
The Regret/Disappointment Scale [PDF]
Judgment and Decision Making, 2008 The present article investigates the effectiveness of methods traditionally used to distinguish between the emotions of regret and disappointment and presents a new method --- the Regret and Disappointment Scale (RDS) --- for assessing the two emotions ...
Francesco Marcatto, Donatella Ferrante
doaj
Prediction of Loneliness on the Basis of Quality of Relationship with God in Young People [PDF]
پژوهشنامه روانشناسی مثبت, 2015 The aim of this study was prediction of loneliness on the basis of quality of relationship with God in young people. Population of the study was 18-35 years old people in Tehran, fromwhich 232 persons were chosen in public places by available sampling ...
fateme ghabezi +3 more
doaj
Illusion and betrayal<br>The city, the poets, or an ethics of truths?
Utrecht Law Review, 2011 A nagging feeling of great expectations turned sour is in the air, at least at this end of the globe. The illusion appears to have been twofold. Those liberals who after the Cold War had imagined finally to see the Western city win over competing forms ...
Igor Stramignoni
doaj +1 more source
Prevalence of Dissociative Experiences in Those Referred to Emergency Psychiatric Centers After Attempting Suicide [PDF]
Hospital Practices and Research, 2018 Background: Dissociation is a symptom that can be related to traumatic childhood events. Dissociation in some cases is categorized in a distinct subgroup from other psychiatric disorders.
Ali Firoozabadi +2 more
doaj +1 more source
Journal of Theoretical and Applied Electronic Commerce Research, 2022 In order to solve the problem of separation between consumer purchase and product experience in online sales, live streaming e-commerce came into being. However, the interaction of streamers is easy to cause consumers’ impulse consumption, which leads to
Guihua Lin +3 more
doaj +1 more source
Sociologie Românească, 2023 The current paper is a review on Septimiu Chelcea’s book Emoții sociale. Despre rușine, vinovăție, regret şi dezamăgire [Social Emotions. About shame, guilt, regret and disappointment], Bucharest, Tritonic Publishing House, 2020. Chelcea’s work captures
Ana Maria Nițu
doaj +1 more source
Frontiers in Human Neuroscience, 2011 Disappointment, the emotion experienced when faced to reward prediction errors, considerably impact decision making. Individuals tend to modify their behavior in an often unpredictable way just to avoid experiencing negative emotions.
Helène eTzieropoulos +5 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source