Results 161 to 170 of about 765,624 (361)

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal   +3 more
wiley   +1 more source

Overcoming the Trade‐Off Between Magnetic Coupling and Electrical Insulation in Soft Magnetic Materials via Nanochain Engineering

open access: yesAdvanced Science, EarlyView.
This study employs a nanochain engineering approach combined with an in situ oxidation strategy to fabricate self‐insulating iron‐based magnetic nanochains, addressing the challenge of balancing magnetic coupling and electrical insulation in soft magnetic materials.
Dingrong Zuo   +8 more
wiley   +1 more source

Social vulnerability and disaster risk reduction needs: perspectives of women

open access: yes
Integration of disaster risk reduction needs and experiences of different groups in the community with the built environment is significant to achieve disaster resilience.
Ginige, K. N.   +2 more
core  

How Disaster Becomes Collective Trauma: Violence and Social Order from a Durkheimian Perspective

open access: yesСоциология власти
This article examines the genesis of a foundational concept in the sociology of trauma — Kai Erikson's theory of collective trauma — which emerged in the context of the post-war American sociology of disaster.
D. A. Bochkov
doaj  

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

open access: yesAdvanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong   +7 more
wiley   +1 more source

Empowering local governments to make a disaster resilient built environment within Sri Lankan Cities

open access: yes, 2013
Urban areas are growing very rapidly all over the world, particularly in developing countries. As a result of rapid urbanisation, the world’s population is increasingly concentrated in large cities leading to unplanned urban development with ...
Amaratunga, Dilanthi   +2 more
core  

Covalent Inhibition of SHMT2 by Gambogic Acid Induces Ferroptosis Through Mitochondrial Collapse in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
In this study, chemoproteomics combined with genetic and functional analyses was integrated to identify SHMT2 as a covalent and functional target of gambogic acid (GA) in triple‐negative breast cancer (TNBC). Further validation demonstrated that GA selectively modifies the Cys241 site of SHMT2, triggering mitochondrial dysfunction, activating the Nrf2 ...
Tong Yang   +15 more
wiley   +1 more source

Post disaster reconstruction as an opportunity for development: women's perspective

open access: yes
In the past few decades many nations have experienced quite a large number of natural disasters. Although they are developing new systems to avoid or reduce the devastation caused by disasters still many countries are struggling to recover.
Amaratunga, Dilanthi   +2 more
core  

The Challenges and Obstacles of Post-Disaster Road Infrastructure Reconstruction in the Pre-Construction Phase [PDF]

open access: yes, 2015
Purpose The reconstruction of road infrastructure in the post-disaster context require different approach when compared with road projects in the normal development context.
Amaratunga, Dilanthi   +2 more
core  

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