Results 171 to 180 of about 765,624 (361)
Advanced Science, EarlyView.In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen +19 more
wiley +1 more source
, 2010 Asia and the Pacific is a region vulnerable to natural hazards of almost every kind - from earthquakes to droughts, from floods to tsunamis. And with the prospect of climate change, the situation could become even more hazardous.
UN.ESCAP +1 more
core
Advanced Science, EarlyView.This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He +10 more
wiley +1 more source
Physics‐Embedded Neural Network: A Novel Approach to Design Polymeric Materials
Advanced Science, EarlyView.Traditional black‐box models for polymer mechanics rely solely on data and lack physical interpretability. This work presents a physics‐embedded neural network (PENN) that integrates constitutive equations into machine learning. The approach ensures reliable stress predictions, provides interpretable parameters, and enables performance‐driven, inverse ...
Siqi Zhan +8 more
wiley +1 more source
Architected Inverse Nacre Hydrogels With High Strength and Crack‐Insensitive Toughness
Advanced Science, EarlyView.Hydrogels hold promise for biomedical and engineering applications, yet their practical use is fundamentally limited by the strength‐toughness trade‐off and poor fatigue resistance. In this study, a bioinspired inverse nacre architecture constructed via a scalable thermo‐calendering process is introduced, which overcomes these classic limitations ...
Haidi Wu +10 more
wiley +1 more source
Disaster resilience in development and humanitarian interventions
The connections between disaster recovery and the resilience of affected communities have become common features of disaster risk reduction programmes since the adoption of The Hyogo Framework for Action (HFA) 2005–2015.
Manyena, Bernard
core
Advanced Science, EarlyView.The symmetry‐driven coexistence of altermagnetism and (anti)ferroelectricity in perovskites shows a strong dimensional dependence. Upon reducing the system from bulk to the two‐dimensional limit, only C‐type antiferromagnetic order retains ferroelectrically switchable altermagnetism, whereas A‐ and G‐type orders become conventional antiferromagnets ...
Zhou Cui +6 more
wiley +1 more source
Knowledge management for disaster resilience: Identification of key success factors
The number of reported disasters has increased steadily over the past century and risen very sharply during the past decade. These bring about the loss of lives, property, employment and damage to the physical infrastructure and the environment. Disaster
Pathirage, C. P. +3 more
core
Disasters and the disaster medicine
Journal of the Korean Medical Association, 2019 Chu Hyun Kim, Eunseog Hong
openaire +1 more source