Results 111 to 120 of about 605,844 (299)

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Real-Time Remote Sensing for Sudden Surface Anomalies: A Review of Principles and Challenges

Space: Science & Technology
Sudden surface anomalies—ranging from earthquakes and floods to wildfires and industrial accidents—pose escalating threats to ecosystems and societies worldwide.
Xing Yan, Hang Lyu, Ziyue Chen, Rui Peng, Jiayi Chen, Junxiao Zou, Weihua Dong, Qiao Wang   +7 more
doaj   +1 more source

Multimedia in Disaster Risk Reduction

Journal of Physics: Conference Series, 2019
Abstract This research aims to find out the comprehension in disaster risk reduction for students of Class IV and analysis the needs of learning media to improve the comprehension in disaster risk reduction. This research applies survey method.
Prajana Marwan Sejati, C. A. Budiningsih, null Pujianto   +2 more
openaire   +1 more source

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

Advanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu, Yajing Liu, Shuman Wang, Xiaoming Bai, Luyun Zhang, Yuwei Liu, Zhiwen Fu, Chen Shi   +7 more
wiley   +1 more source

Scientific challenges in disaster risk reduction for the Sichuan–Tibet Railway

Engineering Geology, 2022
P. Cui, Yong-gang Ge, Shaojun Li, Zhenhong Li, Xi-wei Xu, G. Zhou, Hua-yong Chen, Hao Wang, Yu Lei, Libo Zhou, S. Yi, Chun-hao Wu, Jian Guo, Qi Wang, H. Lan, M. Ding, Junjie Ren, LÜ Zeng, Yuan-fei Jiang, Yan Wang   +19 more
semanticscholar   +1 more source

CD44‐Targeting Hydroxyapatite Nanoparticles (HAP) Induce Mitochondrial Dysfunction‐Driven PANoptosis and Immunogenic Cell Death (ICD) via Ca Overload in Colorectal Cancer

Advanced Science, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains therapeutically challenging due to high metastasis, recurrence, and immunotherapy resistance driven by tumor microenvironment‐mediated immune evasion. Immunogenic cell death (ICD) offers a promising strategy to reshape the immune microenvironment, yet existing ICD inducers suffer from poor targeting efficiency ...
Yao Xiao, Yuxuan Yang, Haosen Qiu, Jia Yang, Hao Liang, Zhaojun Jiang, Xiao Tong, Yongying Li, Qunfeng Huang, Jiaming Wu, Tian Lin, Jiang Yu, Min Liang   +12 more
wiley   +1 more source

Comprehensive Hazard Assessment of Tropical Cyclone-Induced Wind, Rainfall, and Storm Surge: A Case Study of Zhejiang Province, China

International Journal of Disaster Risk Science
Tropical cyclones pose a significant threat to coastal regions through hazard-inducing factors such as wind, rainfall, and storm surge, whose interactions often lead to amplified impacts.
Xinli Liao, Chenna Meng, Kai Tao, Peng Su, Qinmei Han, Lianjie Qin, Wei Xu   +6 more
doaj   +1 more source

Intensified water scarcity in the Asian Water Tower driven by increased water withdrawals

Journal of Hydrology: Regional Studies
Study region: The Asian Water Tower (AWT), encompassing the Tibetan Plateau and surrounding mountain ranges, provides water for nearly 2 billion people.
Yunfei Wang, Aizhong Ye, Fan Yang, Xiaohong Zeng, Huiying Zhu   +4 more
doaj   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

UN Office for Disaster Risk Reduction (2021)

Yearbook of International Disaster Law Online, 2023
Marie Aronsson-Storrier
semanticscholar   +1 more source