Results 121 to 130 of about 605,844 (299)

Unraveling the Power of Disorder: A Bioinspired Cuttlebone Structure With Superior Strength, Energy Absorption and Isotropy

Advanced Science, EarlyView.
Cuttlebone‐inspired architected metamaterials introduce controlled structural disorder to simultaneously enhance strength, energy absorption, and compressive stability. Tunable disorder suppresses shear anisotropy, outperforms periodic lattices, and establishes discrete randomness as a robust route to high‐performance lightweight mechanical ...
Zengqin Shi, Peng Jiang, Xiaoyan Zhu, Suyun Li, Wenqing Wang, Tian Zhao, Rujie He, Ying Li   +7 more
wiley   +1 more source

Integrating hydrological impacts for cost-effective dryland ecological restoration

Communications Earth & Environment
Ecological restoration of fragile drylands involves complex benefit-cost trade-offs. While Systematic Conservation Planning (SCP) provides a foundational framework for this task, its large-scale application in drylands often fails to adequately integrate
Fengyu Fu, Shuai Wang, Xutong Wu, Shiyin Chen, Zimin Tan, ChongChong Ye, José M. Grünzweig   +6 more
doaj   +1 more source

PANX2 Suppresses Lung Adenocarcinoma Progression by Inducing Disulfidptosis and Enhancing Antitumor Immunity

Advanced Science, EarlyView.
ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen, Zhao‐Yu Liu, Gao‐Wen Qu, Run‐Hao Zeng, Wen‐Xia Yao, Yong‐Bing Zhou, Xue Liang, Yu‐Xiong Lai   +7 more
wiley   +1 more source

Diffusion‐Based Generative Model With Scaffold‐Hopping Strategy Yields Highly Potent Bioactive Molecules

Advanced Science, EarlyView.
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang, Xiaoqing Gong, Shukai Gu, Jing Li, Bo Liu, Yanan Tian, Qianqian Zhang, Xiaojun Yao, Huanxiang Liu   +8 more
wiley   +1 more source

How Do Livelihood Assets Affect Subjective Well-Being Under Different Livelihood Strategies? Evidence from Tibetan Rural Households in China

Agriculture
Evaluating rural households’ subjective well-being (SWB) and identifying its determinants is crucial for rural sustainable development. This study takes Diqing Prefecture in the Tibetan region of China as a case, aiming to address two key research ...
Di Lei, Jianjun Jin, Xin Qiu, Dan Liu, Chenyang Zhang   +4 more
doaj   +1 more source

High Fracture Toughness of 1D Copper‐Based MOP Electrode Enables Fast‐Charging Lithium‐Ion Batteries

Advanced Science, EarlyView.
Traditional electrode materials suffer from particle cracking and rapid capacity fade during fast charging, largely originating from their low fracture toughness. This work introduces a one‐dimensional Cu‐based metal–organic polymer, in which strong π‐d conjugation and π–π stacking endow the framework with high fracture toughness, simultaneously ...
Mingli Li, Zhenzhen Wu, Pan Yang, Di Zhao, Mengyang Dong, Muhammad Tayyab Ahsan, Lei Zhang, Shanqing Zhang, Yun Wang   +8 more
wiley   +1 more source

Combining Radiation‐Treated Tumor Vaccines With Mn‐MOF Nanoadjuvants to Amplify Radiation Induced Anti‐Tumor Immune Responses

Advanced Science, EarlyView.
Radiotherapy‐treated tumor membranes are integrated with Mn‐MOF nanoadjuvants to generate Mn@RM, a lymph node‐draining nanovaccine that delivers radiotherapy‐remodeled antigenic components. Mn@RM enhances dendritic cell activation, amplifies T cell‐mediated antitumor immunity, and synergizes with radiotherapy and PD‐1 blockade for combination cancer ...
Yiyu Wang, Qiqi Qi, Dezhong Li, Jingshi Tang, Weifeng Wang, Zushun Xu, Qi Xu, Fangfang Du, Qianyuan He   +8 more
wiley   +1 more source

Global Assessment Report on Disaster Risk Reduction 2021

Global Assessment Report on Disaster Risk Reduction (GAR), 2021

semanticscholar   +1 more source

A Folded, Structure‐Integrated Bimodal Sensor Enabling Non‐Contact and Tactile Perception for Intelligent Robots

Advanced Science, EarlyView.
A foldable bimodal sensor integrates a triboelectric nanogenerator and graphene piezoresistive effect into a monolithic laser‐induced graphene film. It enables synchronous non‐contact and tactile perception, achieving a distance of 110 mm, a sensitivity of 11.2 kPa−1, and a response time of 10 ms.
Weixiong Yang, Yuhan Guo, Mingguang Han, Bin Feng, Yuan Ma, Bingang Xu, Fu Liu, Dan Wang, Pingping Hao, Xilun Ding, Sida Luo   +10 more
wiley   +1 more source

Drought propagation as a nonlinear amplifier of ecohydrological damage

Communications Earth & Environment
Meteorological drought can propagate to soil and ecological droughts, triggering cascading disruptions in ecosystem functioning. However, whether the ecohydrological damage—the sum of standardized vegetation greenness and soil moisture losses—is ...
Zhuoran Qu, Xiaoyan Li, Josep Peñuelas, Deliang Chen, Chiyuan Miao, Yuanhong Deng, Fangzhong Shi, Wenqi Li   +7 more
doaj   +1 more source