Results 21 to 30 of about 282,873 (312)

The Halal Tourism Trajectory, the Emergence and Challenge: The Case of Nanggroe Aceh Darussalam Post-2004 Tsunami

open access: yesHumaniora, 2021
Halal tourism has attracted a lot of attention in contemporary tourism and hospitality research. However, only a few studies have attempted to understand the emerging process and challenges in practicing halal tourism in a specific geographic location ...
Erda Rindrasih
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Natural Disasters—Origins, Impacts, Management

open access: yesEncyclopedia, 2021
Natural hazards are processes that serve as triggers for natural disasters. Natural hazards can be classified into six categories. Geophysical or geological hazards relate to movement in solid earth.
Muhammad T. Chaudhary, Awais Piracha
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Interpretable machine learning for flood susceptibility mapping in the metropolitan region of São Paulo, Southeast Brazil

open access: yesDiscover Geoscience
Accurate flood susceptibility modeling is critical for effective disaster risk management, particularly in rapidly urbanizing regions exposed to extreme precipitation.
Enner Alcântara   +3 more
doaj   +1 more source

The Impact of Earthquakes on Apartment Owners and Renters in Te Whanganui-a-Tara (Wellington) Aotearoa New Zealand

open access: yesApplied Sciences, 2021
Apartment dwelling is on the increase in many cities in Aotearoa New Zealand, including those in earthquake-prone regions. Hence it is important that people working in disaster management and housing improve their understanding on how the living ...
Denise Blake   +3 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Aircraft measurements of aerosol distribution, warm cloud microphysical properties, and their relationship over the Eastern Loess Plateau in China

open access: yesTellus: Series B, Chemical and Physical Meteorology, 2019
In situ aircraft measurements of aerosols and clouds were performed over the eastern Loess Plateau in Shanxi Province, China. The microphysical properties of both aerosols and warm clouds, including aerosol number concentration (Na), particle effective ...
Junxia Li   +5 more
doaj   +1 more source

Positive Affect Is Associated With Better Physical Function in Early Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective This study examined the association between positive affect and physical function in individuals with early rheumatoid arthritis (RA). Methods We analyzed baseline data from 129 adults with early RA (persistent joint symptoms for ≤24 months) and active disease enrolled in the Central Pain in RA 2 (CPIRA‐2) study.
Burcu Aydemir   +9 more
wiley   +1 more source

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