Disc Diffusion and ComASP® Cefiderocol Microdilution Panel to Overcome the Challenge of Cefiderocol Susceptibility Testing in Clinical Laboratory Routine [PDF]
Cefiderocol susceptibility testing represents a major challenge for clinical microbiology. Although disc diffusion showed robustness to test cefiderocol susceptibility, large areas of technical uncertainty (ATU) are reported by current EUCAST breakpoints.
Gabriele Bianco +5 more
doaj +3 more sources
Diffusion of antibiotics in intervertebral disc [PDF]
Delivering charged antibiotics to the intervertebral disc is challenging because of the avascular, negatively charged extracellular matrix (ECM) of the tissue. The purpose of this study was to measure the apparent diffusion coefficient of two clinically relevant, charged antibiotics, vancomycin (positively charged) and oxacillin (negatively charged) in
Frank Eismont +2 more
exaly +4 more sources
Performance of the Disc Diffusion Method, MTS Gradient Tests and Two Commercially Available Microdilution Tests for the Determination of Cefiderocol Susceptibility in Acinetobacter spp. [PDF]
Cefiderocol is a siderophore-conjugated cephalosporin with potent activity against multidrug-resistant Gram-negative pathogens including Acinetobacter baumannii.
Jeannot K +6 more
europepmc +2 more sources
Antibacterial activities against Staphylococcus aureus and Escherichia coli of extracted Piper betle leaf materials by disc diffusion assay and batch experiments. [PDF]
The use of contaminated water by bacteria may cause many diseases, and thus clean water is needed. Chlorine is normally used for the disinfection of wastewater treatment; however, it produces unwanted odors. Using extracted Piper betle (P.
Ngamsurach P, Praipipat P.
europepmc +2 more sources
Disc Diffusion Testing of Azithromycin Against Clinical Isolates of Typhoidal Salmonellae: A Diagnostic Conundrum. [PDF]
Introduction: Typhoid remains a major healthcare problem in low and middle-income countries. The emergence of extremely drug-resistant (XDR) typhoid strains from the Indian subcontinent has led to very limited therapeutic options.
Shoaib M +5 more
europepmc +2 more sources
The EUCAST rapid disc diffusion method for antimicrobial susceptibility testing directly from positive blood culture bottles. [PDF]
Objectives With increasing antimicrobial resistance, rapid antimicrobial susceptibility testing (RAST) becomes important, especially in patients with bloodstream infections.
Jonasson E, Matuschek E, Kahlmeter G.
europepmc +2 more sources
Can disc diffusion susceptibility tests assess the antimicrobial activity of engineered nanoparticles? [PDF]
The use of disc diffusion susceptibility tests to determine the antibacterial activity of engineered nanoparticles (ENPs) is questionable because their low diffusivity practically prevents them from penetrating through the culture media.
Kourmouli A +6 more
europepmc +2 more sources
Performance of the EUCAST disc diffusion method and two MIC methods in detection of Enterobacteriaceae with reduced susceptibility to meropenem: the NordicAST CPE study. [PDF]
Objectives To examine performance of EUCAST disc diffusion and supplementary MIC methods for detection of Enterobacteriaceae with reduced susceptibility to meropenem using EUCAST screening recommendations.
Haldorsen B +13 more
europepmc +3 more sources
Diffusion tensor microscopy of the intervertebral disc anulus fibrosus [PDF]
Morphologically accurate biomechanical models of the intervertebral disc anulus fibrosus (AF) require precise knowledge of its lamellar architecture; however, available methods of assessment are limited by poor spatial resolution or the destructive nature of the technique.
Lori Setton, E W Hsu
exaly +3 more sources
Approximations for diffusion from a disc source
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Philip Broadbridge
exaly +2 more sources

