Results 51 to 60 of about 1,420,968 (287)

Influence of disc height and strain-dependent solute diffusivity on metabolic transport in patient-personalized intervertebral disc models

Frontiers in Bioengineering and Biotechnology
IntroductionIntervertebral disc (IVD) degeneration is a primary contributor to low back pain, with nutritional stress due to the IVD’s avascularity recognized as a key factor.
Zerihun G. Workineh, Estefano Muñoz-Moya, Carlos Ruiz Wills, Dimitrios Lialios, Jérôme Noailly   +4 more
doaj   +1 more source

The effect of sustained compression on oxygen metabolic transport in the intervertebral disc decreases with degenerative changes.

PLoS Computational Biology, 2011
Intervertebral disc metabolic transport is essential to the functional spine and provides the cells with the nutrients necessary to tissue maintenance. Disc degenerative changes alter the tissue mechanics, but interactions between mechanical loading and ...
Andrea Malandrino, Jérôme Noailly, Damien Lacroix   +2 more
doaj   +1 more source

Finite Element Study of Oxygen Diffusion in the Intervertebral Disc

Advances in Bioengineering, 2000
Abstract The intervertebral disc consists of a water-rich extra-cellular matrix which is synthesized and maintained by its cells. The disc is the largest avascular tissue in the body with its cells lying as much as 8mm away from the blood supply.
Sélard, E, Shirazi-Adl, A, Urban, J
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Antibiotic Resistance Pattern of Enterococci Isolates from Nosocomial Infections in Imam Khomeini Hospital, Ahvaz City [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2023
Introduction: Enterococci are opportunistic bacteria that can become pathogenic if colonized. Resistance to commonly used antibiotics by Enterococci causing nosocomial infections is of concern, which necessitates judicious, responsible and evidence-based
Sousan Akrami, Reza Abouali, Rozhin Heidary Lal-Abady, Mohammad Mostafa Olapour, Arshid Yousefi Avarvand   +4 more
doaj  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Comparative evaluation of in vitro activity of tigecycline using the disc diffusion method and the VITEK-2 COMPACT in clinical isolates at a tertiary care cancer center [PDF]

Medical Laboratory Journal
Background: Tigecycline susceptibility testing and reporting remain enigmatic due to the lack of established guidelines. Disc diffusion, as a method of performing susceptibility testing, is more widely accepted worldwide due to its ease of use.
Sujata Lall, Vivek Bhat, Sanjay Biswas, Navin Khattry   +3 more
doaj  

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Cube-based diffusion algorithm [PDF]

, 2007
We study molecular diffusion in (linear) nanopores with different types of roughness in the so-called Knudsen regime. Knudsen diffusion represents the limiting case of molecular diffusion in pores, where mutual encounters of the molecules within the free
Kärger, Jörg, Zschiegner, Stephan, Bunde, Armin, Russ, Stefanie   +3 more
core   +1 more source

Diffusion of small solutes into the intervertebral disc: as in vitro study

Biorheology, 1978
By comparing results obtained in vivo on penetration of (35S) sulphate and (3H) methyl glucose into the intervertebral disc of adult dogs, with those calculated using Fick’s law, and diffusion and partition coefficients obtained in vitro, diffusion was shown to be the main mechanism for transport of small solutes into the intervertebral disc.
Urban, J, Holm, S, Maroudas, A
openaire   +3 more sources