Results 51 to 60 of about 1,424,908 (288)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Influence of disc height and strain-dependent solute diffusivity on metabolic transport in patient-personalized intervertebral disc models

Frontiers in Bioengineering and Biotechnology
IntroductionIntervertebral disc (IVD) degeneration is a primary contributor to low back pain, with nutritional stress due to the IVD’s avascularity recognized as a key factor.
Zerihun G. Workineh, Estefano Muñoz-Moya, Carlos Ruiz Wills, Dimitrios Lialios, Jérôme Noailly   +4 more
doaj   +1 more source

The effect of sustained compression on oxygen metabolic transport in the intervertebral disc decreases with degenerative changes.

PLoS Computational Biology, 2011
Intervertebral disc metabolic transport is essential to the functional spine and provides the cells with the nutrients necessary to tissue maintenance. Disc degenerative changes alter the tissue mechanics, but interactions between mechanical loading and ...
Andrea Malandrino, Jérôme Noailly, Damien Lacroix   +2 more
doaj   +1 more source

Antibiotic Resistance Pattern of Enterococci Isolates from Nosocomial Infections in Imam Khomeini Hospital, Ahvaz City [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2023
Introduction: Enterococci are opportunistic bacteria that can become pathogenic if colonized. Resistance to commonly used antibiotics by Enterococci causing nosocomial infections is of concern, which necessitates judicious, responsible and evidence-based
Sousan Akrami, Reza Abouali, Rozhin Heidary Lal-Abady, Mohammad Mostafa Olapour, Arshid Yousefi Avarvand   +4 more
doaj  

Finite Element Study of Oxygen Diffusion in the Intervertebral Disc

Advances in Bioengineering, 2000
Abstract The intervertebral disc consists of a water-rich extra-cellular matrix which is synthesized and maintained by its cells. The disc is the largest avascular tissue in the body with its cells lying as much as 8mm away from the blood supply.
Sélard, E, Shirazi-Adl, A, Urban, J
openaire   +2 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Comparative evaluation of in vitro activity of tigecycline using the disc diffusion method and the VITEK-2 COMPACT in clinical isolates at a tertiary care cancer center [PDF]

Medical Laboratory Journal
Background: Tigecycline susceptibility testing and reporting remain enigmatic due to the lack of established guidelines. Disc diffusion, as a method of performing susceptibility testing, is more widely accepted worldwide due to its ease of use.
Sujata Lall, Vivek Bhat, Sanjay Biswas, Navin Khattry   +3 more
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cube-based diffusion algorithm [PDF]

, 2007
We study molecular diffusion in (linear) nanopores with different types of roughness in the so-called Knudsen regime. Knudsen diffusion represents the limiting case of molecular diffusion in pores, where mutual encounters of the molecules within the free
Kärger, Jörg, Zschiegner, Stephan, Bunde, Armin, Russ, Stefanie   +3 more
core   +1 more source