Results 41 to 50 of about 61,621 (260)

Antibacterial Potency of Extracted Essential Oils of Some Plant Species against Common Gram-Positive and Gram-Negative Bacteria

King Khalid University Journal of Health Sciences, 2021
Background: In the last decades, due to the rapid emergence of multidrug resistant pathogens, the antibiotic-resistance phenomenon has become a global health crisis. Therefore, there is a need to find new remedies against pathogenic microbes. Objectives:
Gaffar Sarwar Zaman
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Influence of disc height and strain-dependent solute diffusivity on metabolic transport in patient-personalized intervertebral disc models

Frontiers in Bioengineering and Biotechnology
IntroductionIntervertebral disc (IVD) degeneration is a primary contributor to low back pain, with nutritional stress due to the IVD’s avascularity recognized as a key factor.
Zerihun G. Workineh, Estefano Muñoz-Moya, Carlos Ruiz Wills, Dimitrios Lialios, Jérôme Noailly   +4 more
doaj   +1 more source

The effect of sustained compression on oxygen metabolic transport in the intervertebral disc decreases with degenerative changes.

PLoS Computational Biology, 2011
Intervertebral disc metabolic transport is essential to the functional spine and provides the cells with the nutrients necessary to tissue maintenance. Disc degenerative changes alter the tissue mechanics, but interactions between mechanical loading and ...
Andrea Malandrino, Jérôme Noailly, Damien Lacroix   +2 more
doaj   +1 more source

Finite Element Study of Oxygen Diffusion in the Intervertebral Disc

Advances in Bioengineering, 2000
Abstract The intervertebral disc consists of a water-rich extra-cellular matrix which is synthesized and maintained by its cells. The disc is the largest avascular tissue in the body with its cells lying as much as 8mm away from the blood supply.
Sélard, E, Shirazi-Adl, A, Urban, J
openaire   +2 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Comparative evaluation of in vitro activity of tigecycline using the disc diffusion method and the VITEK-2 COMPACT in clinical isolates at a tertiary care cancer center [PDF]

Medical Laboratory Journal
Background: Tigecycline susceptibility testing and reporting remain enigmatic due to the lack of established guidelines. Disc diffusion, as a method of performing susceptibility testing, is more widely accepted worldwide due to its ease of use.
Sujata Lall, Vivek Bhat, Sanjay Biswas, Navin Khattry   +3 more
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A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Antibiotic Resistance Pattern of Enterococci Isolates from Nosocomial Infections in Imam Khomeini Hospital, Ahvaz City [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2023
Introduction: Enterococci are opportunistic bacteria that can become pathogenic if colonized. Resistance to commonly used antibiotics by Enterococci causing nosocomial infections is of concern, which necessitates judicious, responsible and evidence-based
Sousan Akrami, Reza Abouali, Rozhin Heidary Lal-Abady, Mohammad Mostafa Olapour, Arshid Yousefi Avarvand   +4 more
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