Results 81 to 90 of about 1,420,968 (287)

Improving Turnaround Times for Routine Antimicrobial Sensitivity Testing Following European Committee on Antimicrobial Susceptibility Testing Methodology in Patients with Bacteraemia

Antibiotics
Background/Objectives: Bacteraemia can be fatal without antibiotic intervention. Antibiotic Susceptibility Testing (AST) provides the necessary information for targeted antibiotic therapy; however, the traditional method using disc diffusion can take ...
Raewyn Edmondson, Kordo Saeed, Steve Green, Matthew O’Dwyer   +3 more
doaj   +1 more source

Computational investigation of sulphate diffusion into the dog disc

2011 18th Iranian Conference of Biomedical Engineering (ICBME), 2011
We proposed a model to investigate the transient diffusion of drug (sulphate) into the intervertebral disc. Using finite element method, drug diffusion was simulated and the concentration of diffused drug in each region of disc including Nucleus pulpous (NP), Inner annulus fibroses (IA), and Outer annulus fibroses (OA) was measured.
Motaghinasab, S, Shirazi-Adl, A, Urban, J, Parnianpour, M, Hoviattalab, M   +4 more
openaire   +2 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Effects of oxidation and hot corrosion in a nickel disc alloy [PDF]

, 2008
This paper describes work to study oxidation and hot corrosion damage in nickel disc alloy RR1000. Oxidation damage has been characterised via mass change data from thermogravimetric analyses at temperatures from 700 to 800 ºC and cyclic oxidation ...
Encinas-Oropesa, Adriana, J.R. Nicholls, N.J. Simms, Hardy, M. C., A.J. Leggett, A. Encinas-Oropesa, M.C. Hardy, Leggett, A. J., Nicholls, John R., G.L. Drew, Drew, G. L., Simms, Nigel J.   +11 more
core   +1 more source

Effective diffusion tensor computed by homogenization [PDF]

, 2013
The convergence of the long-time apparent diffusion tensor of diffusion magnetic resonance imaging (dMRI) to the effective diffusion tensor obtained by mathematical homogenization theory was considered for two-compartment geometric models containing non ...
Grebenkov, Denis, Poupon, Cyril, Li, Jing-Rebecca Li, Bihan, Denis Le, Nguyen, Dang Van   +4 more
core   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

disc-re/Contrail-Statistics: Contrail Statistics Tool

, 2022
This analysis tool evaluates the atmospheric contrail formation conditions based on ECMWF ERA-5 Reanalysis data and helps to obtain an overview of the frequency of contrail formation over the last 10 years at different altitudes, seasons and ...
disc-re
core   +1 more source

Electroacupuncture attenuates intervertebral disc degeneration by upregulating aquaporins via the cAMP/PKA pathway

Journal of Orthopaedic Surgery and Research
Background Intervertebral disc degeneration (IVDD) is characterized by a decrease in extracellular matrix (ECM) and water loss, which is a major cause of low back pain (LBP). Electroacupuncture (EA) has long been used to relieve LBP in IVDD.
Min Wang, Jia-Bao Huang, Jing Zou, Guo-fu Huang   +3 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source