Results 31 to 40 of about 61,621 (260)

Intervertebral disc degeneration instigates vertebral endplate remodeling and facet joint pathology in a large animal model

European Cells & Materials
Although the intervertebral discs are the most studied region of the spinal motion segment with respect to their degeneration and contributions to back pain, it is becoming increasingly evident that degeneration of adjacent structures including the facet
SE Gullbrand, BS Orozco, M Fainor, K Meadows, R Hilliard, M Boyes, S Mahindroo, RL Mauck, DM Elliott, TP Schaer, HE Smith   +10 more
doaj   +1 more source

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo, Melissa Gerstle, Leah Cheng, Richard Cooper, Katherine Coyne, Claire Dusa, Naomi E. Joffe, Diana Schwarz, Sarah Steltz, Akiko Shimamura, Kasiani C. Myers, Thea Quinton   +11 more
wiley   +1 more source

Hall diffusion and the magnetorotational instability in protoplanetary discs [PDF]

Monthly Notices of the Royal Astronomical Society, 2012
The destabilising effect of Hall diffusion in a Keplerian disc allows the MRI to occur for much lower ionisation levels than would otherwise be possible. However, simulations suggest that the consequences for the saturated state are not as significant as suggested by the linear instability.
Mark Wardle, Raquel Salmeron
openaire   +4 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Bioevaluation of antibacterial potential of Sarpgandha (Rauwolfia serpentina)

Environment Conservation Journal, 2009
The  in vitro  antibacterial  activity of Rauwolfia serpentina  plant  extract has been  investigated against  Escherichia  coli, Staphylococcus  aureus,  Salmonella  typhi and  Klebsiella  pneumoniae using the  disc  diffusion  method.  The  alcoholic  
Vishal Upadhayay, Deepika, Padma Singh, P. Kaushik   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Performance of disc diffusion and E-test on different Muller-Hinton agar media plates and ComASPⓇ and Bruker UMICⓇ Cefiderocol Microdilution Panels for Cefiderocol susceptibility testing in carbapenem-resistant Pseudomonas aeruginosa

Journal of Global Antimicrobial Resistance
BACKGROUND: Cefiderocol is effective against carbapenem-resistant Pseudomonas aeruginosa (CRPA) and requires standardized iron concentrations for accurate susceptibility testing. This study evaluated the performance of two commercial broth microdilution (
Stefano Mancini, Helena Seth Smith, Natalia Kolesnik Goldmann, Vladimira Hinic, Tim Roloff, Muhammad Ali Syed, Oliver Nolte, Adrian Egli   +7 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Comparison of four diagnostic methods for detection of methicillin resistant Staphylococcus aureus

Iranian Journal of Microbiology, 2014
Background and Objectives: Methicillin-resistant Staphylococcus aureus (MRSA) is a well-known pathogen with a worldwide distribution. Given the increasing rate of MRSA infections, implementing of reliable, accurate and rapid testing for diagnosis of MRSA
Mohammad Reza Pourmand, Sepideh Hassanzadeh, Rahil Mashhadi, Emran Askari   +3 more
doaj